FAMILIAL MELANOMA RESEARCH CLINIC (FMRC)

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 据估计，2000年在美国出生的每75人中就有一人会在一生中患上黑素瘤。 报告表明，8-12%的黑素瘤发生在家族群体中，并且认为与黑素瘤有一级亲属的那些人具有2-3倍的发展黑素瘤的风险。 我们已经建立了一个高风险的黑色素瘤诊所（家族性黑色素瘤研究诊所，FMRC），作为一个“核心”设施，提供一个机制，调查家庭与黑色素瘤的遗传风险。该诊所是在先前存在的犹他州大学高风险乳腺癌和家族性结肠癌诊所的基础上建立的，该诊所为遗传性癌症的研究提供了完善的模型。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. It is estimated that one out of every 75 people born in the U.S. in the year 2000 will get a melanoma in his/her lifetime. Reports indicate that between 8-12% of melanomas occur within family groups and those people having a first degree relative with melanoma are considered to have a 2-3 fold increased risk of developing melanoma. We have established a high-risk melanoma clinic (Familial Melanoma Research Clinic, FMRC) that acts as a "core" facility to provide a mechanism for investigation of families with an inherited risk of melanoma. This clinic was patterned after the preexisting University of Utah High Risk Breast and Familial Colon Cancer Clinics that provided well-established models for the investigation of inherited cancers.