ADOLESCENT EMOTIONS PROJECT

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者的研究机构。 青春期的自杀行为标志着以后自杀的重大风险，并可能代表边缘型人格障碍（BPD）发展的前兆。准自杀和BPD理论认为，情绪失调是自我伤害行为的基础，自我伤害行为有助于调节压倒性的负面情绪。然而，没有研究已经彻底探讨了一个情绪失调模型的准自杀，包括这一特点的认知和生理措施。拟议的研究将比较parasuicidal青少年与正常对照组和临床对照组与重性抑郁症（n=25/组）的行为和生理措施的情绪调节。青少年和他们的父母将完成情绪调节和精神病理学的自我报告措施。生理评估将与父母和青少年在基线，情感唤起电影剪辑从“冠军”，和解决问题的讨论。生理指标包括皮肤电反应（EDR）、呼吸性窦性心律不齐（RSA）和心脏射血前期（PEP）。青少年还将完成地塞米松抑制试验（DST），这是自杀风险的既定生物标志物。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Parasuicidal behavior in adolescence marks significant risk for later suicide and may represent a precursor to the development of borderline personality disorder (BPD). Theories of parasuicide and BPD suggest that emotion dysregulation underlies the act of self-harm, which serves to regulate overwhelming negative affect. However, no studies have thoroughly explored an emotion dysregulation model of parasuicide, inculding both cognitive and physiological measures of this trait. The proposed research will compare parasuicidal teens with normal controls and a clinical comparison group with major depressive disorder (n=25/group) on behavioral and physiological measures of emotion regulation. Adolescents and their parent will complete self-report measures of emotion regulation and psychopathology. Physiological assessments will be conducted with both the parent and adolescent during baseline, an emotionally evocative film clip from "The Champ," and a problem-solving discussion. Physiological indices include electrodermal responding (EDR), respiratory sinus arrhythmia (RSA), and cardiac pre-ejection period (PEP). Adolescents will also complete a dexamethasone suppression test (DST), which is an established biological marker of suicide risk.