Washington University Intellectual and Developmental Disabilities Research Center

描述(由申请人提供)：华盛顿大学智力和发育障碍研究中心(WUIDDRC)的目标是促进尖端创新，以理解和治疗智力和发育障碍。中心将为44名杰出的研究人员提供核心资源，这些研究人员开展了62个与智力和发育障碍有关的项目。WUIDDRC有四个主要目标： 1.通过新的研究机会、卓越的研究设施、智力激发和跨学科合作，促进对发育障碍的研究。WUIDDRC将专注于研究三个相辅相成但本质上相互关联的研究主题领域的研究人员：大脑连接、遗传学和环境影响。 2.提供高效、成本效益高、最先进的服务和设施，通过五个核心：管理、生物统计和信息学、人类临床研究、脑成像和动物模型研究，提高WUIDDRC调查人员的质量和生产率。 3.建立一个强大和高效的基础设施，以支持与发育障碍有关的研究活动。WUIDDRC将吸引现有和新的研究人员，以增加新的知识和开发影响IDD的创新。其战略是在一大批领先的研究科学家中为新的合作创造机会。 4.建立WUIDDRC调查人员、其他组织研究人员、发育障碍儿童临床提供者和当地社区之间有效、定期、频繁的沟通和协调机制。 位于圣路易斯的华盛顿大学在神经科学方面有着长期的卓越记录。但在整合和协调针对智力和发育障碍的研究方面，它在基础设施方面存在差距。WUIDDRC将使其调查人员容易获得现有的、复杂的和新颖的方法，以弥合这些差距。一个实际的结果是，将当地人才集中在一个紧迫的健康问题上，这为促进对人脑发育的理解提供了相当大的潜力。WUIDDRC将通过创造一个合作的、跨学科的环境来促进进步，这将加速直接影响智力和发育障碍儿童的研究。

DESCRIPTION (Provided by Applicant): The goal of the Washington University Intellectual and Developmental Disabilities Research Center (WUIDDRC) is to promote cutting-edge Innovation to understand and treat intellectual and developmental disabilities. WUIDDRC would provide core resources for 44 outstanding investigators conducting 62 projects related to intellectual and developmental disabilities. WUIDDRC has four main goals: 1. Promote research on developmental disabilities, through new research opportunities, excellence in research facilities, intellectual stimulation, and Interdisciplinary collaborations. WUIDDRC will focus on investigators studying three complementary but fundamentally interrelated research theme areas: cerebral connectivity, genetics, and environmental influences. 2. Provide efficient, cost-effective, state-of-the-art services and facilities to enhance the quality and productivity of WUIDDRC investigators through five cores: Administration, Biostatistics and Informatics, Human Clinical Studies, Brain Imaging, and Animal Model Studies. 3. Create a strong and efficient infrastructure to support research activities related to developmental disabilities. WUIDDRC will attract established and new investigators to add new knowledge and develop innovations impacting IDD. The strategy is to create opportunities for novel collaboration in a large pool of leading research scientists. 4. Build a mechanism for effective, regular, and frequent communication and coordination among WUIDDRC investigators, researchers in other organizations, clinical providers for children with developmental disabilities, and the local community. Washington University in St. Louis has a long record of excellence in neuroscience. But it has gaps in infrastructure to integrate and coordinate research targeted to intellectual and developmental disabilities. WUIDDRC would make existing, sophisticated, and novel approaches readily accessible to its investigators to close these gaps. A practical outcome is to focus local talent on a pressing health problem that offers considerable potential to advance understanding of human brain development. WUIDDRC will stimulate advances by creating a collaborative, interdisciplinary environment that will accelerate research to directly impact children with intellectual and developmental disabilities.