权益分类	功能权益	普通用户	{{item.name}}会员
{{category.name}}	{{benefitItem.name}}

Washington University Intellectual and Developmental Disabilities Research Center

华盛顿大学智力与发育障碍研究中心

基本信息

批准号：
8706926
负责人：
JOHN N. CONSTANTINO
金额：
$ 80.05万
依托单位：
WASHINGTON UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2010
资助国家：
美国
起止时间：
2010-08-01 至 2015-09-17
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8706926
关键词：
Animal Model Animals Area Biometry Brain Brain imaging Centers of Research Excellence Cerebral Palsy Cerebrum Child Clinical Clinical Research Collaborations Communication Communities Complement Congresses Development Developmental Disabilities Discipline Environment Genetic Goals Growth and Development function Health Human Infant Informatics Knowledge Learning Mental Retardation Mental Retardation and Developmental Disabilities Research Centers Methods Nature Neurosciences Outcome Patients Philosophy Physicians Prevention Productivity Provider Research Research Activity Research Infrastructure Research Personnel Research Project Grants Research Support Resources Scientist Services Strategic Planning Talents Targeted Research Time Universities Washington base cost effective follow-up improved innovation intellectual and developmental disability interdisciplinary collaboration neuroimaging novel novel strategies research facility translational study

项目摘要

DESCRIPTION (Provided by Applicant): The goal of the Washington University Intellectual and Developmental Disabilities Research Center (WUIDDRC) is to promote cutting-edge Innovation to understand and treat intellectual and developmental disabilities. WUIDDRC would provide core resources for 44 outstanding investigators conducting 62 projects related to intellectual and developmental disabilities. WUIDDRC has four main goals: 1. Promote research on developmental disabilities, through new research opportunities, excellence in research facilities, intellectual stimulation, and Interdisciplinary collaborations. WUIDDRC will focus on investigators studying three complementary but fundamentally interrelated research theme areas: cerebral connectivity, genetics, and environmental influences. 2. Provide efficient, cost-effective, state-of-the-art services and facilities to enhance the quality and productivity of WUIDDRC investigators through five cores: Administration, Biostatistics and Informatics, Human Clinical Studies, Brain Imaging, and Animal Model Studies. 3. Create a strong and efficient infrastructure to support research activities related to developmental disabilities. WUIDDRC will attract established and new investigators to add new knowledge and develop innovations impacting IDD. The strategy is to create opportunities for novel collaboration in a large pool of leading research scientists. 4. Build a mechanism for effective, regular, and frequent communication and coordination among WUIDDRC investigators, researchers in other organizations, clinical providers for children with developmental disabilities, and the local community. Washington University in St. Louis has a long record of excellence in neuroscience. But it has gaps in infrastructure to integrate and coordinate research targeted to intellectual and developmental disabilities. WUIDDRC would make existing, sophisticated, and novel approaches readily accessible to its investigators to close these gaps. A practical outcome is to focus local talent on a pressing health problem that offers considerable potential to advance understanding of human brain development. WUIDDRC will stimulate advances by creating a collaborative, interdisciplinary environment that will accelerate research to directly impact children with intellectual and developmental disabilities.

描述（由申请人提供）：华盛顿大学智力和发育障碍研究中心（WUIDDRC）的目标是促进尖端创新，以了解和治疗智力和发育障碍。该中心将为44名杰出的调查人员提供核心资源，开展62个与智力和发展残疾有关的项目。妇女参与国际发展中心有四个主要目标： 1.通过新的研究机会，卓越的研究设施，智力刺激和跨学科合作，促进对发育障碍的研究。 WUIDDRC将专注于研究三个互补但基本上相互关联的研究主题领域的研究人员：大脑连接，遗传学和环境影响。 2.提供高效，具有成本效益，最先进的服务和设施，通过五个核心提高WUIDDRC研究人员的质量和生产力：管理，生物统计学和信息学，人类临床研究，脑成像和动物模型研究。 3.建立一个强大而有效的基础设施，以支持与发育障碍有关的研究活动。 WUIDDRC将吸引新老研究人员，增加新知识，开发影响IDD的创新。该战略是在一大批领先的研究科学家中创造新的合作机会。 4.建立一个有效的机制，定期，和WUIDDRC调查员之间的频繁沟通和协调，在其他组织的研究人员，为发展障碍儿童的临床服务提供者，和当地社区。圣路易斯的华盛顿大学在神经科学方面有着悠久的历史。但它在基础设施方面存在差距，无法整合和协调针对智力和发育障碍的研究。 WUIDDRC将使现有的，复杂的，新颖的方法容易接近其调查人员，以弥补这些差距。一个实际的结果是将当地人才集中在一个紧迫的健康问题上，这为促进对人类大脑发育的理解提供了相当大的潜力。 WUIDDRC将通过创造一个协作的跨学科环境来促进进步，这将加速研究，直接影响智力和发育障碍儿童。

项目成果

期刊论文数量（22）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Socio-demographic factors related to parent engagement in the NICU and the impact of the SENSE program.

DOI：
10.1016/j.earlhumdev.2021.105486
发表时间：
2021-12
期刊：
Early human development
影响因子：
2.5
作者：
Whitehill L;Smith J;Colditz G;Le T;Kellner P;Pineda R
通讯作者：
Pineda R

Axon density and axon orientation dispersion in children born preterm.

DOI：
10.1002/hbm.23227
发表时间：
2016-09
期刊：
Human brain mapping
影响因子：
4.8
作者：
Kelly CE;Thompson DK;Chen J;Leemans A;Adamson CL;Inder TE;Cheong JL;Doyle LW;Anderson PJ
通讯作者：
Anderson PJ

Neurologic Injury in Acidemic Term Infants.

DOI：
10.1055/s-0036-1597135
发表时间：
2017-06
期刊：
American journal of perinatology
影响因子：
2
作者：
Cahill AG;Mathur AM;Smyser CD;Mckinstry RC;Roehl KA;López JD;Inder TE;Macones GA
通讯作者：
Macones GA

Neuroimaging in Tourette Syndrome: Research Highlights From 2014-2015.

DOI：
10.1007/s40474-015-0062-6
发表时间：
2015-12
期刊：
Current developmental disorders reports
影响因子：
2
作者：
Greene DJ;Schlaggar BL;Black KJ
通讯作者：
Black KJ

Very preterm birth: maternal experiences of the neonatal intensive care environment.

DOI：
10.1038/jp.2014.43
发表时间：
2014-07
期刊：
JOURNAL OF PERINATOLOGY
影响因子：
2.9
作者：
Woodward, L. J.;Bora, S.;Clark, C. A. C.;Montgomery-Hoenger, A.;Pritchard, V. E.;Spencer, C.;Austin, N. C.
通讯作者：
Austin, N. C.