Support of Yerkes National Primate Research Center

本申请寻求五年的基础赠款（P51 RR 00165）的持续支持， 埃默里大学耶基斯国家灵长类动物研究中心。Yerkes NPRC的运作是 在NCRR计划指南（第六版）的指导下。据记载， 在本报告所述期间取得了重大进展，并在此介绍 未来五年的全面计划（2011年5月1日至2016年4月30日）。本申请的目的是 符合我们的使命，即提供开展研究所需的全面研究基础设施。 一个主要由校外赠款和其他资助机制资助的研究项目，主要来自 国家卫生研究院要求继续为以下全部或部分组成部分提供P51资金，以支持 中心的科学使命：行政管理，包括科学领导和全面管理， 商业服务、信息技术、人力资源和公共事务;设施 管理;研究资源，包括兽医，动物护理，群体管理， 动物记录和行为管理;以及服务病理学、环境卫生和 安全和研究服务，为外部研究人员提供全面支持;以及 科学服务核心：生物标志物，成像和病毒学。还寻求支持四个科学 部门：微生物学和免疫学，神经药理学和神经疾病， 发展和认知神经科学和行为神经科学和精神疾病。 此外，还要求对五个试点研究项目提供支持，以使中心研究人员能够 收集初步数据，并在可能导致随后 外部支持。还寻求为两项资源增加赠款提供支助。最后，支持是 在改善和现代化下要求加强基础设施的要素。的 耶基斯NPRCs的中心目标是支持一个研究计划，重点是科学问题的相关 提供资源基础设施和专门知识， 兽医专业来支持这样的计划。Yerkes的其他目标是增强 中心作为核心研究人员和全国科学家的资源的能力， 在国际上，以及提供教育和培训机会。

This application seeks five years of continued support for the Base Grant (P51 RR00165) for the Yerkes National Primate Research Center of Emory University. The operation ofthe Yerkes NPRC is guided by the NCRR Program Guidelines for NPRCs (Sixth Edition). The YNPRC, as documented herein, has recorded substantial progress in the present reporting period, and also here presents comprehensive plans for the next five years (5/1/2011 - 4/30/2016). The objectives in this application are aligned to our mission of providing the comprehensive research infrastructure required to conduct a research program largely funded by extramural grants and other funding mechanisms, chiefly from NIH. Continued P51 funding is requested for all or part ofthe following components to support the Center's scientific mission: Administration, including scientific leadership and overall management, business services, information technology, human resources, and public affairs; Facilities Management; Research Resources, including veterinary medicine, animal care, colony management, animal records, and behavioral management; as vi/ell as service pathology, environmental health and safety, and research services to provide comprehensive support to outside investigators; and three Science Service Cores: Biomarkers, Imaging, and Virology. Support is also sought for four scientific divisions: Microbiology and Immunology, Neuropharmacology and Neurologic Diseases, Developmental and Cognitive Neuroscience and Behavioral Neuroscience and Psychiatric Disorders. Additionally, support is requested for five Pilot Research Projects to allow Center investigators to collect preliminary data and develop improved methodologies in areas likely to lead to subsequent external support. Support is also sought for two resource enhancement grants. Finally, support is requested under Improvement and Modernization to enhance elements ofthe infrastructure. The Yerkes NPRCs central goal is to support a research program focused on scientific problems relevant to human health, and to provide the resource infrastructure and expertise in appropriate scientific and veterinary specialties to support such a program. Additional Yerkes goals are to enhance the Center's ability to serve as a resource to core investigators and to scientists nationally and internationally, as well as to provide educational and training opportunities.