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Validating Area-Level Behavioral Profiles for Cancer Disparities Research

验证癌症差异研究的区域级行为概况

基本信息

批准号：
7455950
负责人：
Ann Carroll Klassen
金额：
$ 16.4万
依托单位：
JOHNS HOPKINS UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2007
资助国家：
美国
起止时间：
2007-07-01 至 2010-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7455950
关键词：
Address Age Area Attitude Behavior Behavioral Biological Process Breast Cancer Burden Case Study Censuses Characteristics Chronic Disease Colorectal Communities County Data Data Reporting Demography Disease Distal Electronics Expenditure Future Geographic Locations Goals Health Health Status Health behavior Healthcare Individual Investigation Lung Malignant Neoplasms Marketing Maryland Measurement Measures Medical Surveillance Methodology Methods Modeling Monitor National Health Interview Survey Pathway interactions Pattern Population Poverty Privacy Prostate Proxy Research Research Personnel Resources Risk Role Services Social Environment Social Sciences Socioeconomic Status Subgroup Testing Washington Work base behavior influence behavioral/social science cancer health disparity cancer risk cancer site commercial application consumer behavior demographics falls improved innovation neoplasm registry social socioeconomics theories tool

项目摘要

DESCRIPTION (provided by applicant): Census-derived socioeconomic measures have wide acceptance among social science researchers both as small-area proxies for individual-level information when direct measurement is not feasible, as well as important constructs in their own right in specifically ecological models investigating the effect of the social environment and contextual resources on health. Many extensions of demographic data are utilized successfully in commercial areas such as marketing, including "geodemographics," the segmentation and definition of small geographic areas based on both demographics and consumer behavior. However, the utility of commercially prepared area-level behavioral data for health research is largely unknown. The aims of this exploratory R21 investigation are to test the utility of area-level behavioral consumer profile data in explaining geographic disparities in cancer burden, and to refine area-level behavioral data methodologies for future studies. Specifically, this project will: 1) use commercially prepared area-level consumer profile data to build a geographic coverage for Maryland on specific cancer-related behaviors and a composite cancer risk profile, and test the construct validity of these measures by statistically modeling their similarity to high-quality individually reported data from the CLUE studies of Washington County residents age 21 and older, 2) examine the predictive validity of these measures, when added to socioeconomic and healthcare access measures, on excess cancer burden for four major cancer sites (breast, colorectal, prostate, and lung), using cases reported in 2000 to the Maryland Cancer Registry, and 3) contribute to the methods and theory for understanding social and behavioral influences on spatial patterns of disparities in cancer and other diseases, with the long-term goal of improving tools for monitoring progress in addressing these health inequities. This research addresses the call for proposals in behavioral and social science methodology to build methods for multi-method, multi-level research, and to develop methods which are reliable and valid in diverse and high priority populations. The innovative methodology, if validated by the proposed work, offers a potential tool for moving from highly confidential and reactive methods of behavioral surveillance to less costly, widely applicable methodologies. This proposed exploratory research informs the State of Maryland of geographic areas with excess risk for one or several population subgroups, overall and above what might be anticipated by non-geographic characteristics, and clinically, it may suggest subgroups of the population, geographic areas, or communities for whom specific types of services warranted, to address high risk or high need. For social science researchers in health, it also offers a possible tool for investigating and understanding community-level health behaviors, and it may suggest areas for more specific inquiry to researchers focusing on cancer disparities.

描述（由申请人提供）：人口普查衍生的社会经济措施在社会科学研究人员中得到广泛接受，既可以作为直接测量不可行时个人层面信息的小区域代理，也可以作为调查社会环境和环境资源对健康影响的特定生态模型中的重要结构。人口统计数据的许多扩展在商业领域如市场营销中被成功利用，包括“地理人口统计”，即基于人口统计和消费者行为的小地理区域的分割和定义。然而，商业准备的地区一级的行为数据的效用在很大程度上是未知的健康研究。这项探索性的R21调查的目的是测试地区层面的行为消费者资料数据在解释癌症负担的地理差异方面的效用，并为未来的研究改进地区层面的行为数据方法。具体而言，该项目将：1）使用商业准备的地区级消费者概况数据来建立马里兰州特定癌症相关行为的地理覆盖范围和复合癌症风险概况，并通过对这些措施与来自华盛顿县21岁及以上居民的CLUE研究的高质量个体报告数据的相似性进行统计建模来测试这些措施的结构有效性，2）检查这些指标的预测有效性，当加入社会经济和医疗保健可及性指标时，对四个主要癌症部位的过度癌症负担（乳腺癌、结直肠癌、前列腺癌和肺癌），使用2000年向马里兰州癌症登记处报告的病例，和3）有助于理解社会和行为对癌症和其他疾病差异空间模式的影响的方法和理论，其长期目标是改进用于监测解决这些卫生不平等方面进展情况的工具。这项研究解决了在行为和社会科学方法论的建议，以建立多方法，多层次的研究方法，并制定方法，这是可靠的，有效的，在不同的和高优先级的人群。创新的方法，如果通过拟议的工作验证，提供了一个潜在的工具，从高度机密和反应性的行为监测方法，成本较低，广泛适用的方法。这项拟议的探索性研究向马里兰州通报了一个或多个人群亚组总体风险过高的地理区域，以及超出非地理特征预期的风险，并且在临床上，它可能建议人群亚组、地理区域或社区，以满足特定类型的服务，以解决高风险或高需求。对于健康领域的社会科学研究人员来说，它也为调查和理解社区层面的健康行为提供了一个可能的工具，它可能会为关注癌症差异的研究人员提供更具体的调查领域。