Center for Point-of-Care Technologies Research for Sexually Transmitted Diseases

我们中心的长期目标包括通过开发和更好地使用护理点(POC)测试来解决美国和资源匮乏环境中的性病和艾滋病毒流行问题，从而解决健康不平等问题并改善个人的性健康。我们的具体目标是1)提供中心的行政结构，以确保大型、复杂的中心及时实现其目标。2)从临床医生、最终用户和其他适当的利益相关者那里进行综合的临床需求评估和健康影响评估，以期推进POC测试设计、开发、3)与物理和生化科学家、计算科学家和系统工程师合作，a)为原型开发项目提供探索性技术，b)测试更成熟的POCT，以确保检测沿着从概念阶段到临床测试阶段的管道进行合理的进展。4)在临床情况下和在资源贫乏的国家测试成熟的POC测试，以便在急诊科、家庭测试等环境中更好地使用POC测试，并促进此类测试的临床接受度和使用，从而改善健康，特别是对于那些经历健康差距和不平等的人。5)以迭代的方式向不同职业水平的技术开发人员提供关于临床和流程问题以及与POC设备开发相关的需求的培训，以及为资源贫乏环境中的科学家提供培训，并就POC技术的开发和潜在影响对相关利益攸关方进行教育。这些目标和目的将通过一个有效的管理部分来实现，确定POC用户的需求，培训科学家，资助科学家和工程师开发原型和成熟的POC技术，以及在不同的临床环境中进行POC测试的试点测试和实施，这将导致用于诊断性疾病的POC测试的商业化和使用，以改善美国和世界其他地区个人的性健康。

The long-term goals of our center include addressing the epidemics of STDs and HIV in the U.S. and in resource-poor settings by development and better use of Point-of-Care (POC) tests, so as to address health inequity and improve the sexual health of individuals Our specific aims are 1) Provide a Center administrative structure to ensure that the large, complex Center achieves its goals in a timely manner.2) Conduct integrated clinical needs assessments and health impact assessments from clinicians, end-users, and other appropriate stakeholders, with the anticipation to advance and inform the field of POC testing design, development, and utilization by disseminating this information to the technology development community.3) Collaborate with physical and biochemical scientists, computational scientists, and systems engineers on a) exploratory technology for prototype development projects and b) for testing of more mature POCTs to insure a logical progression of assays along a pipeline from the concept stage to the clinical testing stage. 4) To test mature POC assays in clinical situations and in resource poor countries in order to enhance use of POC tests in settings such as emergency departments, home testing and to advance clinical acceptance and use of such tests and thus improve health especially for those experiencing health disparities and inequities.5) Provide training to technology developers across various career levels on clinical and process issues as well as needs related to the development of POC devices in an iterative fashion, as well as provide training for scientists in resource poor settins and education of relevant stakeholders on the development and potential impact of POC technologies. These goals and aims will be accomplished by an effective administrative component, ascertaining needs of users of POC, training of scientists, funding scientists and engineers for development of prototype and mature POC technologies, and pilot testing and implementation of POC tests in diverse clinical settings, which will lead to the commercialization and use of POC tests for diagnosing STDs in order to improve the sexual health of individuals in the United States and the rest of the world.