TR&D 3: Enriching the Data Stream: MR and PET in Concert

TRD3项目摘要 我们高级成像创新与研究中心(CAI2R)的广泛使命是为 合作翻译研究团队共同开发高影响力的生物医学成像 技术，最终目标是改变日常临床实践。技术研究和 开发(R&D)项目3旨在利用磁共振成像(MRI) 和正电子发射断层扫描(PET)，以改进和通知基于成像的组织评估 疾病中的结构和功能。使用现代机器学习方法和其他使能硬件 和软件，我们将把这两种互补的成像模式结合成截然不同的感觉 各种形式被组合成一个多方面的多感官流。我们工作的具体成果将包括 1)MR和PET运动校正的新技术和新技术；2)提取运动校正的新算法 来自MR和PET收购的补充信息；3)为组合定制的新示踪剂 MR-PET扫描，而不仅仅是针对传统的分子靶点；以及4)新的手段 阐明组织的内在结构和功能。

TRD3 Project Summary The broad mission of our Center for Advanced Imaging Innovation and Research (CAI2R) is to bring together collaborative translational research teams for the development of high-impact biomedical imaging technologies, with the ultimate goal of changing day-to-day clinical practice. Technology Research and Development (TR&D) Project 3 aims to exploit unique synergies between Magnetic Resonance Imaging (MRI) and Positron Emission Tomography (PET), in order to improve and inform imaging-based evaluations of tissue structure and function in disease. Using modern methods of machine learning and other enabling hardware and software, we will combine these two complementary imaging modalities much as distinct sensory modalities are combined into a multifaceted multisensory stream. Concrete outcomes of our work will include 1) new techniques and technologies for motion correction in MR and PET; 2) new algorithms for the extraction of complementary information from MR and PET acquisitions; 3) new tracers that are tailored for combined MR-PET scanning rather than merely being addressed at traditional molecular targets; and 4) new means of elucidating the intrinsic structure and function of tissue.