The Data Management and Statistics Core

项目摘要 数据管理和统计核心（DMSC）一直是该中心的一个积极和关键的组成部分， 城市环境中的儿童哮喘（CCAUE）超过15年，在以下方面发挥关键作用：（1） 整合来自多个来源的多种类型的研究数据;（2）确保运行的复杂过程 多个临床研究是无缝的;（3）制定和执行复杂时间的统计分析计划， 系列和空间数据;（4）在多个研究者之间引导数据和分析结果的讨论， 环境评估核心（EAC）工作人员每周数据管理会议;以及（5）制定 支持CCAUE项目的统计方法。在这次儿童中心的更新中，DMSC将 在过去15年的基础设施和经验的基础上，继续发挥同样的作用。DMSC 工作人员深入了解所有临床项目的细节，以及行政 核心（AC），EAC和实验室，处理生物标本。这些知识有助于 DMSC管理这些组件之间发生的数据流的能力。如果没有灾害管理服务中心， 管理和分析必须在每个研究的基础设施内进行，这使得很难 利用以前为其他研究开发的数据管理系统， 在过去的15年里，DMSC还通过以下方式提供对高级统计支持的即时访问： 中心研究人员和工作人员。通过集中资源支持灾害管理服务中心，可以支持专职工作人员， 继续创建满足多种研究需求以及AC、EAC需求的系统， 和支持实验室。此外，这些系统提供了集成所有 儿童中心的组成部分，因为许多已经到位的系统是具体的 旨在促进儿童中心各组成部分之间的数据传输、管理和分析。

Project Summary The Data Management and Statistics Core (DMSC) has been an active and key component of the Center for Childhood Asthma in the Urban Environment (CCAUE) for more than 15 years, serving a critical role in: (1) integrating multiple types of study data from multiple sources; (2) ensuring that the complex process of running multiple clinical studies is seamless; (3) developing and executing statistical analysis plans for complex time- series and spatial data; (4) leading discussion of data and analysis results among multiple investigators and Environmental Assessments Core (EAC) staff at weekly data management meetings; and (5) developing statistical methods to support CCAUE's projects. In this renewal of the Children's Center, the DMSC will continue to serve this same role, building on its infrastructure and experience from the past 15 years. DMSC staff has an in-depth understanding of the details of all of the clinical projects, as well as the Administrative Core (AC), EAC, and laboratories, which process the biologic specimens. This knowledge facilitates the DMSC's ability to manage the flow of data that occurs among these components. Without a DMSC, data management and analysis would have to be conducted within each study's infrastructure, making it difficult to leverage data management systems previously developed for other studies and that have been built and refined over the past 15 years. The DMSC also provides immediate access to advanced statistical support by Center investigators and staff. By pooling resources to support a DMSC, dedicated staff can be supported and continue to create systems which serve the needs of multiple studies, as well as the needs of the AC, the EAC, and the support laboratories. Further, these systems provide the underlying structure that integrates all components of the Children's Center, as many of the systems that are already in place are specifically designed to facilitate transfer, management and analysis of data among Children's Center components.