Clinical and Translational Science Institute

联系PD/PI：Grandis、Jennifer Rubin 第1部分总体摘要 加州大学旧金山分校临床和转化科学研究所（CTSI）建立了一个协调的平台， 转化研究，成功地改善，整合和扩展研究服务和基础设施， 并制定了全面的培训计划。该计划扩大了服务和基础设施， 与区域合作伙伴合作，特别是加州CTSA（UC BRAID）的5所大学， 改善了旧金山弗朗西斯科湾区弱势居民的健康状况。在这项基础工作的基础上， CTSI现在建议通过开发和连接新兴技术来利用这些优势， 提高进行跨学科、多地点临床和转化的质量、效率和成本 research.这一总体目标将通过协调信息学和技术与传统知识来实现。 研究基础设施，由高效的培训计划支持，以及传统上对 团队科学这些活动还将整合CTSI的区域合作伙伴UC的专业知识， BRAID、CTSA国家网络和PCORnet。UCSF CTSI总体具体目标将侧重于： 1.情报学与科研创新 2.社区参与和团队科学; 3.翻译工作队伍的发展和试点翻译和临床研究; 4.专家咨询和监管知识与支持; 5.整合特殊人群和参与者与临床的相互作用; 6.为NCATS的试验和招募创新中心提供联络; 7.产品开发和 8.精准医疗 项目摘要/摘要第267页 联系PD/PI：Grandis、Jennifer Rubin

Contact PD/PI: Grandis, Jennifer Rubin Part 1 Overall Abstract The UCSF Clinical and Translational Science Institute (CTSI) has built a coordinated platform for clinical and translational research, successfully improved, integrated, and extended research services and infrastructure, and created comprehensive training programs. The program has expanded services and infrastructure by collaborating with regional partners, notably the 5 University of California CTSAs (UC BRAID), and measurably improved the health of vulnerable residents in the San Francisco Bay Area. Building on this foundational work, the CTSI now proposes to leverage these strengths by developing and linking emerging technologies to improve the quality, efficiency, and cost of conducting interdisciplinary, multisite clinical and translational research. This overarching goal will be achieved by coordinating informatics and technology with traditional research infrastructure, supported by highly effective training programs, and a traditionally strong focus on team science. These activities will also integrate expertise from and scale to CTSI's regional partners, UC BRAID, the CTSA national network, and PCORnet. The UCSF CTSI Overall Specific Aims will focus on: 1. Informatics and Research Innovation; 2. Community Engagement and Team Science; 3. Translational Workforce Development and Pilot Translational and Clinical Studies; 4. Expert Consultation and Regulatory Knowledge and Support; 5. Integrating Special Populations and Participant and Clinical Interactions; 6. Providing Liaison to NCATS' Trial and Recruitment Innovation Centers; 7. Product Development, and 8. Precision Medicine. Project Summary/Abstract Page 267 Contact PD/PI: Grandis, Jennifer Rubin