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Developmental Research Project Program

Developmental Research Project Program
发展研究项目计划
批准号:
9461564
负责人:
SHELLEY LUSETTI
金额:
$189.92万
依托单位国家:
美国
项目类别:
财政年份:
2018
资助国家:
美国
项目状态:
已结题
起止时间:
2018-04-01 至 2019-03-31

项目摘要

项目成果

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中文摘要
翻译
NM-INBRE DRPP为有前途的新的和早期职业研究人员提供关键支持,是他们发展研究职业方向的决定性因素。这些项目涉及大脑和行为健康、癌症、心血管和代谢疾病、儿童健康、环境健康、传染病和免疫等领域的重大生物医学问题和关键健康问题。DRPP科学的质量是杰出的,导致在高影响力的期刊上发表文章,并为具有抗癌特性的新型潘帕他汀和刚性素类似物申请专利。鼓励研究合作的努力取得了成功,在目前的资助期内,23%的出版物涉及2个或更多NM-INBRE参与者之间的合作,预计这一趋势将在持续的计划中增加。尽管资金环境困难,调查人员还是成功地竞争了外部联邦赠款,包括最近的R 01、R21、R 03和R15奖项。DRPP对合作机构产生了重大影响,例如圣胡安学院,这是一所位于四角地区的两年制副学士学位授予机构,拥有大量美国原住民学生,在那里,NM-INBRE支持的研究活动被用来证明NSF赠款的竞争性申请是合理的,以改造研究空间并安装一个洁净室,该洁净室得到了资助,现在支持研究项目。DRPP项目的框架也服务于让学生接触研究经验的主要目标,这种影响将通过扩大项目组合来增加机会。
英文摘要
The NM-INBRE DRPP provides critical support for promising new and early career investigators, and is a determining factor in the direction of their developing research careers. These projects address significant biomedical questions and critical health problems in the areas of Brain and Behavioral Health; Cancer; Cardiovascular and Metabolic Diseases; Child Health; Environmental Health; Infectious Disease and Immunity. The quality of the DRPP science is outstanding, resulting in publications in high impact journals, and pending patents for novel pancratistatin and rigidin analogues with anticancer properties. Efforts to encourage research collaboration have been successful, during the current funding period 23% of the publications have involved collaborations between 2 or more NM-INBRE participants, and this trend is expected to increase in the continuing program. Investigators have been successful in competing for external federal grants, in spite of the difficult funding environment, including recent R01, R21, R03, and R15 awards. The DRPP has made significant impacts on the partner institutions, such as San Juan College, a two-year associate degree-granting institution in the four-corners region with a large Native American student population, where the research activity supported by the NM-INBRE was leveraged to justify a competitive application for an NSF grant to remodel the research space and install a clean room that was funded and now supports research projects. The framework of DRPP projects also serve the primary objective of exposing students to research experiences, and this impact will continue with increased opportunities through an expanded portfolio of projects.
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Administrative Core
Repair of Damaged Chromosomes Mediated by the Bacterial RecN Protein
Repair of Damaged Chromosomes Mediated by the Bacterial RecN Protein
Repair of Damaged Chromosomes Mediated by the Bacterial RecN Protein
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