Nanopatch immunisation against pandemic influenza: improved immune responses at a reduced dose.

开发一种新的流感疫苗接种方法，使标准疫苗的效力是传统注射器注射的100倍。Nanopatch是由硅片制成的，上面布满了微纳尺度的尖峰。它可以无痛地将疫苗沉积在皮肤表面下。在老鼠身上的实验表明，即使是很小的疫苗有效载荷输送到皮肤上，也会产生良好的免疫反应。Nanopatch疫苗接种系统预计将在几年内准备好进行临床试验。

Development of a new way to vaccinate against influenza that will make standard vaccines 100 times more potent than conventional syringe injection. The Nanopatch is made from a silicon wafer, bristling with micro-nanoscale spikes. It painlessly deposits vaccine under the skin surface. Experiments in mice show that even a small vaccine payload delivered to the skin generates good immune responses. The Nanopatch vaccination system is expected to be ready for clinical trials within a few years.