Predoctoral Training in Neurobiology

项目摘要/摘要 这是一份支持加州大学旧金山分校学生成功培训计划的申请书。 神经科学研究生课程。该计划可以追溯到1977年，旨在提供高度的 在实验神经科学的理论和实践，统计方法， 量化技能发展、数据分析和管理以及科学交流。 完成这一使命需要一个致力于应对挑战的组织框架 现代神经科学训练所固有的。为此，我们最近对我们的培训计划进行了全面修改，以 适应我们快速发展的领域。第一年的课程致力于一门核心课程，重点是 现代神经科学的基础，然后是负责任的科学行为的课程。此外, 学生进行3次实验室轮换，定期与他们的研究生导师会面，讨论职业目标， 最终在第一年结束时进入了一个论文实验室。在第二年，学生们开始他们的研究， 参加高级课程，包括科学写作、实验设计和数据分析等课程。 他们还为资格赛考试做准备。第三年及以后的时间专注于开发、指挥、 在他们的论文实验室完成并发表独立研究项目。学生们每年见面两次 与他们的论文委员会合作一年，并与他们的PI一起决定何时取得足够的进展，以 毕业了。然后，学生们准备并提交一篇书面论文，并与所有委员会一起举行公开的退出研讨会。 与会人员，经论文委员会一致同意授予博士学位。 神经科学计划目前有62名培训教师，分布在14个系、中心和附属机构 研究所。项目成员资格会定期审查，并仅限于致力于指导的教职员工 和教学，参与计划活动，并保持严格的研究计划。几乎所有领域的 神经科学被我们教员的研究兴趣所涵盖。实习生参加每周一次的 研讨会系列和每周师生研究进展研讨会，以及年度计划 撤退。在过去，T32培训补助金一直是我们计划最重要的支柱 在过去的40年里取得了成功；它被用来支持学生在第一和第二年的学习 在他们进入候选人资格并开始全日制博士论文研究之前。我们招收 每年大约15-18名学生，其中大约一半将由这笔培训补助金支持 在他们的头两年。我们的主要目标是培养不同的学生群体，使他们了解 现代神经科学的方法，通过传授成功所需的技能、知识和领导技能 在一系列与神经科学相关的职业中。NIH的支持对我们继续提供 研究生所需要的教育，他们将成为各自领域的未来领导者。

Project Summary/Abstract This is an application to support a successful training program for students admitted to the UCSF Neuroscience Graduate Program. The program, which dates back to 1977, is designed to provide a highly rigorous training in both the theory and practice of experimental neuroscience, statistical methodologies, quantitative skills development, data analysis and management, and scientific communication. Accomplishing this mission requires an organizational framework dedicated to addressing the challenges inherent in modern neuroscience training. To this end, we have recently overhauled our training program to adapt to our rapidly evolving field. The first year curriculum is devoted to a core course focused on the fundamentals of modern neuroscience, followed by a course in the responsible conduct of science. In addition, students perform 3 laboratory rotations and meet regularly with their graduate advisor to discuss career goals, culminating with entry into a thesis lab at the end of the first year. In year two, students begin their research, take advanced courses, including courses covering scientific writing, experimental design, and data analysis. They also prepare for qualifying examinations. Years three and beyond are focused on developing, conducting, completing, and publishing an independent research project in their thesis laboratory. Students meet 2 times a year with their thesis committee and determine, along with their PI, when enough progress has been made to graduate. Students then prepare and submit a written thesis and give a public exit seminar with all committee members present, with the PhD degree being granted upon the unanimous approval of the thesis committee. The Neuroscience Program currently has 62 training faculty across 14 departments, centers, and affiliated institutes. Program membership is periodically reviewed, and is restricted to faculty who commit to mentorship and teaching, participate in program activities, and maintain a rigorous research program. Virtually all areas of neuroscience are encompassed by the research interests of our faculty. The trainees attend a weekly seminar series and weekly student-faculty research-in-progress seminars, as well as an annual program retreat. In the past, the T32 training grant has been the single most important pillar underlying our program’s success over the past 40 years; it was used to support students during their first and second years of study before they have advanced to candidacy and initiated full-time Ph.D. thesis research. We enroll approximately 15-18 students per year, of whom approximately half would be supported by this training grant during their first two years. Our primary objective is to train a diverse student body in the concepts and methods of modern neuroscience by imparting the skills, knowledge, and leadership skills needed to succeed across a range of neuroscience-related careers. NIH support is essential for us to continue to provide graduate students with the education they will need to become future leaders in their field.