Necroptosis and Human Disease

细胞死亡是一个正常的过程，允许我们重要组织的生长和防御。一种细胞死亡，坏死性凋亡，其特征是细胞肿胀和破裂，引发炎症。坏死是从结肠炎到关节炎等疾病的一个关键特征，并导致中风和心脏病发作后的大脑和心脏损伤。了解坏死性细胞死亡将为那些患有这些毁灭性疾病的人的新疗法铺平道路。

Cell death is a normal process that permits the growth and defense of our vital tissues. One kind of cell death, necroptosis, is characterised by the swelling and bursting of cells, triggering inflammation. Necroptosis is a key feature of illnesses ranging from colitis to arthritis, and contributes to the brain and heart damage that follows strokes and heart attacks. Understanding necroptotic cell death will pave the way for new therapies for those who suffer from these devastating conditions.