T32 Training Program in Mechanisms and Innovation in Vascular Disease
T32 Training Program in Mechanisms and Innovation in Vascular Disease
批准号:
10669582
负责人:
Nicholas James Leeper
金额:
$47.93万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2010
资助国家:
美国
项目状态:
未结题
起止时间:
2010-07-01 至 2025-06-30
中文摘要
项目摘要
这项T32转化性血管研究培训计划建立在斯坦福大学
心血管研究所,提供宝贵的独特和创新的职业发展机会
给一群在血管疾病管理方面有前途的早期职业研究人员。它支持NHLBI
使命是开发预防、诊断和治疗心血管疾病的新的综合战略,同时在
同时实现其教育目标,培训未来的领导者基础、翻译和应用血管
研究。这款T32是斯坦福大学唯一在全校范围内开发下一代翻译的努力
血管调查员。该计划的目标包括严格的科学方法培训,批判性分析,
在高度协作的多学科环境中进行逻辑推理和独立思考。实习生发展
血管研究专长的重点领域,并接触到广泛的互补性研究
技巧。导师提供口头和书面指导,是大学合作和高效协作的典范
沟通和灌输对负责任的研究行为的尊重。我们过去的实习生继续
成为一流学术机构和行业的独立研究人员,并成为
血管研究领域。
该计划建议继续培训6名多学科血管研究的博士后研究员。研究员
每年都被任命到这个T32,强烈鼓励他们寻求自己的资金再多几年
作为该计划传授的技能的一部分。到目前为止,已有31名学员从该计划中受益,其中包括18名学员
妇女和4个代表不足的少数族裔。目前有六人正在接受培训。评估表明,
对计划的满意度。该项目由医学教授曹菲利普博士(联系人Pi)指导,
斯坦福大学医学院;弗吉尼亚州帕洛阿尔托卫生保健精准医学副参谋长
斯坦福大学血管内科主任、外科和内科教授Nicholas Leeper博士说。
行政和项目管理支持由斯坦福大学的一支专门的教育团队提供
心血管研究所。由来自广泛领域的斯坦福大学高级教职员工组成的内部咨询委员会
学科和由血管医学和研究领域的领先专家组成的外部咨询委员会
美国在监督这一培训计划的进展方面发挥着至关重要的作用,提供持续的支持和建议
视需要而定。我们的首要目标是培训下一代血管研究人员,以及
以促进他们转变为多产和成功的学术和行业领导者。
英文摘要
Project Summary
This T32 translational vascular research training program builds on the capabilities of the Stanford
Cardiovascular Institute, which provides valuable unique and innovative professional development opportunities
to a diverse group of promising early career investigators in vascular disease management. It supports NHLBI’s
mission to develop novel integrative strategies to prevent, diagnose, and treat cardiovascular diseases, while at
the same time fulfilling its educational goal to train tomorrow’s leaders in basic, translational, and applied vascular
research. This T32 is Stanford's only University-wide effort to develop the next generation of translational
vascular investigators. The program goals include rigorous training in the scientific method, critical analysis,
logical reasoning and independent thinking in a highly collaborative, multidisciplinary setting. Trainees develop
a focused area of vascular research expertise and are exposed to a wide range of complementary research
techniques. Mentors model collegial and productive collaboration provide guidance in oral and written
communication and instill respect for the responsible conduct of research. Our past trainees have gone on to
become independent researchers in premier academic institutions and in industry and are emerging leaders in
the field of vascular research.
The program proposes to continue training 6 postdoctoral fellows in multidisciplinary vascular research. Fellows
are appointed to this T32 annually, with a strong encouragement to seek their own funding for additional years
as part of the skills imparted by the program. 31 trainees so far have benefited from this program, including 18
women and 4 underrepresented minorities. Six are currently in training. Evaluations suggest a high degree of
satisfaction with the program. The Program is directed by Philip Tsao, PhD (Contact PI), Professor of Medicine,
Stanford University School of Medicine; Associate Chief of Staff -Precision Medicine, VA Palo Alto Health Care
System, and Nicholas Leeper, MD, Professor of Surgery and Medicine; Chief, Vascular Medicine, Stanford.
Administrative and program management support is provided by a dedicated team of educators in the Stanford
Cardiovascular Institute. An Internal Advisory Board consisting of senior Stanford faculty from a broad range of
disciplines and an External Advisory Board consisting of leading experts in vascular medicine and research in
the US play a vital role in monitoring the progress of this training program, providing ongoing support and advice
as needed. Our overarching goal is to train the next generation of investigators in vascular research, and
to facilitate their transition into productive and successful academic and industry leaders.
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DOI:
10.1242/bio.20146767
发表时间:
2014-02-15
期刊:
Biology open
影响因子:
2.4
作者:
[Li Y, Hao H, Tzatzalos E, Lin RK, Doh S, Liu LF, Lyu YL, Cai L]
通讯作者:
Cai L
A novel pacing maneuver to verify the postpacing interval minus the tachycardia cycle length while adjusting for decremental conduction: Using "dual-chamber entrainment" for improved supraventricular tachycardia discrimination.
一种新颖的起搏操作,用于验证起搏后间隔减去心动过速周期长度,同时调整递减传导:使用“双腔夹带”改善室上性心动过速辨别。
DOI:
10.1016/j.hrthm.2018.11.021
发表时间:
2019
期刊:
Heart rhythm
影响因子:
5.5
作者:
[Kaiser,DanielW, Nasir,JavedM, Liem,LBing, Brodt,Chad, Motonaga,KaraS, Ceresnak,ScottR, Turakhia,MintuP, Dubin,AnneM]
通讯作者:
Dubin,AnneM
Mechanisms of vascular endothelial growth factor-induced pathfinding by endothelial sprouts in biomaterials.
血管内皮生长因子诱导生物材料中内皮芽寻路的机制。
DOI:
10.1089/ten.tea.2011.0323
发表时间:
2012
期刊:
Tissue engineering. Part A
影响因子:
--
作者:
[Shamloo,Amir, Xu,Hui, Heilshorn,Sarah]
通讯作者:
Heilshorn,Sarah
DOI:
10.1016/j.cmet.2018.01.005
发表时间:
2018-03-06
期刊:
Cell metabolism
影响因子:
29
作者:
[Mardinoglu A, Wu H, Bjornson E, Zhang C, Hakkarainen A, Räsänen SM, Lee S, Mancina RM, Bergentall M, Pietiläinen KH, Söderlund S, Matikainen N, Ståhlman M, Bergh PO, Adiels M, Piening BD, Granér M, Lundbom N, Williams KJ, Romeo S, Nielsen J, Snyder M, Uhlén M, Bergström G, Perkins R, Marschall HU, Bäckhed F, Taskinen MR, Borén J]
通讯作者:
Borén J
DOI:
10.1002/adhm.201300620
发表时间:
2014-05
期刊:
Advanced healthcare materials
影响因子:
10
作者:
[Nakayama KH, Hou L, Huang NF]
通讯作者:
Huang NF
共 87 条
Clonal expansion, resistance to efferocytosis and innate immunity in atherosclerosis
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批准号:10543819
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资助金额:$85.4万
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财政年份:2019
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负责人:Nicholas James Leeper
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依托单位:
Clonal expansion, resistance to efferocytosis and innate immunity in atherosclerosis
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批准号:10327636
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The role of CDKN2B in efferocytosis and atherosclerosis
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The paradoxical role of CDKN2B in blood vessel sprouting and maturation
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批准号:9173040
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资助金额:$46.66万
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财政年份:2014
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依托单位:
The paradoxical role of CDKN2B in blood vessel sprouting and maturation
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批准号:8968859
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项目类别:
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资助金额:$46.49万
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财政年份:2014
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负责人:Nicholas James Leeper
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The paradoxical role of CDKN2B in blood vessel sprouting and maturation
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批准号:8792819
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The role of CDKN2B in AAA disease
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批准号:8466362
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资助金额:$13.32万
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财政年份:2012
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负责人:Nicholas James Leeper
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依托单位:
The role of CDKN2B in AAA disease
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批准号:8661240
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项目类别:
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资助金额:$13.32万
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财政年份:2012
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批准号:8298769
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资助金额:$13.32万
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财政年份:2012
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T32 Training Program in Mechanisms and Innovation in Vascular Disease
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批准号:10450636
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项目类别:
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资助金额:$46.27万
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财政年份:2010
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负责人:Nicholas James Leeper
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T32 Training Program in Mechanisms and Innovation in Vascular Disease
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批准号:10021162
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The role of the apelin-APJ pathway in vascular wall disease
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依托单位:
海外基金