Clinical and Translational Research Infrastructure Network IDeA-CTR

MW CTR-IN程序--摘要 多样化的西部山区(MW)人口继续受到高失业率的困扰 与其他地区相比，健康差距(HD)和较低的预期寿命比率 US1号。微波临床和转译研究基础设施网络(CTR-IN) 成立于2013年。在过去的4年里，我们创造了一个有影响力的 与我们的13兆瓦大学合作伙伴一起建立的变革性研究网络 在7个机构发展奖(IDEA)州中按地理位置解决 6-10年影响兆瓦人口的健康差距。然而，尽管这片辽阔的领土 和整体不足的地区性临床研究基础设施，我们成功地 在过去4年中创建并实施了功能强大的CTR-IN计划，该计划已 在13所兆瓦大学中播撒了一种具有变革意义的CTR文化。在过去的4年中 多年来，我们创建并实施了4个高生产率的核心，包括试点赠款， 生物统计学、专业发展和管理，使我们能够 在未来5年，重点解决我们兆瓦地区的健康差距问题。 因此，我们建议通过以下方式扩大MW CTR-IN计划的原始任务 进一步加强7兆瓦IDEA州的研究基础设施，以便开展 严格的临床和转化研究(CTR)侧重于健康差异。 我们建议的三个主要主题如下：(1)CTR关注MW Health 差距；(2)优先考虑初级教师的专业发展 调查人员；以及(3)为其他IDEA项目和大学提供领导 兆瓦地区。因此，我们提出四个主要目标，将我们的活动集中在健康上 通过严格的CTR，兆瓦地区的差距如下： 目标1.加强基础设施和人力资源，以进行严格的 在我们的13个主要公立大学合作伙伴中，我们的7个Idea MW中的CTR。 目标2.关注我们不同人群所经历的健康差距，例如 在我们的7个IDEA MW中，医疗服务不足的和/或农村社区通过 我们的CTR计划。 目标3.增强我们的创意大学和研究人员的开发能力 具有竞争力的临床和转化性研究赠款，用于后续的校外资助。 目标4.加强临床和翻译工作的协作和协调 在我们7兆瓦的IDEA州和我们的13兆瓦大学合作伙伴内部和之间的活动。

MW CTR-IN Program -- Abstract The diverse Mountain West (MW) population continues to be plagued by high rates of health disparities (HD) and lower life expectancy rates when compared to the rest of the US1. The MW Clinical and Translational Research Infrastructure Network (CTR-IN) was established in 2013. During the last 4 years, we have created an impactful and transformative research network with our 13 MW university partners located geographically among 7 Institutional Development Award (IDeA) states to address the health disparities affecting the MW population in Year 6-10. Yet, despite this huge territory and an overall insufficient regional clinical research infrastructure, we have successfully created and implemented a highly functional CTR-IN program in the last 4 years that has seeded a transformative culture of CTR among the 13 MW universities. Over the last 4 years, we created and implemented 4 highly productive Cores consisting of Pilot Grants, Biostatistics, Professional Development and Administration that have positioned us to focus on addressing the health disparities in our MW region for the next 5 years. Hence, we propose to expand the original mission of the MW CTR-IN Program by further enhancing the research infrastructure in the 7 MW IDeA states for the conduct of rigorous clinical and translational research (CTR) focused on health disparities. The 3 major themes of our proposal are as follows: (1) CTR focused on the MW health disparities; (2) Priority on the professional development of the MW junior faculty investigators; and (3) Providing leadership to the other IDeA programs & Universities in the MW region. Hence, we are proposing 4 major aims to focus our activities on the health disparities in the MW region through rigorous CTR as follows: Aim 1. Enhance the infrastructure and human resources required to conduct rigorous CTR in our 7 IDeA MW states at our 13 major public university partners. Aim 2. Focus on the health disparities experienced by our diverse populations such as the medically underserved and/or rural communities in our 7 IDeA MW states through our CTR programs. Aim 3. Enhance the ability of our IDeA universities and investigators to develop competitive clinical and translational research grants for subsequent extramural funding. Aim 4. Foster increased collaboration and coordination of clinical and translational activities within and across our 7 MW IDeA states and our 13 MW university partners.