Training Core

培训核心-项目总结：MDSRC培训核心的主要目标是1)培训下一个 新一代科学家/临床医生在肌肉领域进行转化性研究和临床研究 营养不良症(MD)，2)为患者及其家人提供教育和外展活动，3)作为 肌营养不良症临床和研究社区与患者倡导之间的联络人 组织。我们提出了一个培训核心，以1)提供翻译的指导性研究培训计划 以及临床研究和伦理，将激励和准备有才华的新研究人员来解决关键问题 MD患者的需求，2)开发项目，让太平洋西北部和我们的研究人员参与进来 MD研究的附属机构，以及3)提高公众和患者社区对MD临床和 相关的研究工作。培训研究人员的成本继续上升，同时为支持培训提供资金 这些项目一直停滞不前。我们在培训计划中缓解这一问题的方法将是 利用华盛顿大学(UW)其他部门/机构和私营部门合作伙伴提供 学员奖学金，并利用现有的威斯康星大学资源提供教育机会。我们的成员 MDSRC参与了威斯康星大学干细胞和再生医学研究所、翻译肌肉中心 研究(CTMR)和转化健康科学研究所(IIHS)；我们中的许多人也是 生物工程、心血管训练计划(BCTP)、细胞和分子生物学计划 生物化学研究生课程，所有这些课程都提供实习生课程，供我们使用。除了 MDSRC专题研讨会，突出来自威斯康星州大学和外部机构的演讲者，跨计划研讨会 培训计划将扩大我们可以为学员提供的培训。ITS的职业发展 课程、神经病学和神经学系拨款撰写课程，以及跨学院生物医学研究 诚信计划将完善对临床医生和研究人员的培训。我们的MDSRC还将发起一项年度 向所有学科的所有级别的学生/实习生开放工作坊，教育他们关于肌肉营养不良和 我们进行的研究，我们赞助了一系列研讨会。要鼓励基本用户之间的交互 科学家和临床医生，我们的研究实验室与华盛顿大学和西雅图的丙二醛诊所和临床医生密切合作 儿童医院(Wang)，以及与澳大利亚大学附属项目2的医学中心 堪萨斯州(斯塔特兰)、内华达州(琼斯)和罗切斯特(塔维尔)。我们还组织研讨会，让患者和 他们的家人与临床医生和研究人员举行联合会议，增加了我们的外联活动，并为 教育和影响受训者关于他们的观点和关切。总体而言，我们的计划是培育一个 鼓励参与的沟通、协作和职业发展指导环境 在肌肉营养不良症研究中。这一目标将与对家庭的外联和沟通相结合，并通过 与患者倡导团体合作，传播研究和临床最新情况。

Training Core – Project Summary:The major goals of this MDSRC Training Core are to 1) train the next generation of scientists/clinicians to perform translational research and implement clinical studies in muscular dystrophies (MD), 2) provide educational and outreach activities to patients and their families, and 3) to serve as a liaison between the muscular dystrophy clinical and research communities and patient advocacy organizations. We propose a training core to 1) provide a mentored research training program in translational and clinical research and ethics that will inspire and prepare talented new investigators to address the critical needs of individuals with MD, 2) develop programs that engage researchers in the Pacific Northwest and our affiliates in MD research, and 3) increase awareness in the public and patient communities of MD clinical and related research efforts. The cost of training researchers continues to rise while funding to support training programs has remained stagnant. Our approach to mitigate this issue within our training program will be to leverage other University of Washington (UW) departments/institutes and private sector partners to provide trainee fellowships, and to use established UW resources to provide educational opportunities. Members of our MDSRC are involved in UW’s Institute of Stem Cell and Regenerative Medicine, Center for Translational Muscle Research (CTMR), and the Institute of Translational Health Sciences (ITHS); many of us are also part of the Bioengineering, Cardiovascular Training Program (BCTP), Cellular and Molecular Biology Program & the Biochemistry graduate programs, all of which provide trainee programs that we utilize. In addition to an MDSRC-specific symposium highlighting speakers from UW and outside institutions, cross program symposia and training programs will expand the training we can provide our trainees. ITHS’s career development programs, ITHS and Dept of Neurology grant writing programs, and a cross-institute Biomedical Research Integrity program will round out the training for clinician and researchers. Our MDSRC will also initiate an annual workshop open to students/trainees at all levels in all disciplines to educate them on muscular dystrophy and the research we undertake, and we sponsor a seminar series. To encourage interactions between basic scientists and clinicians, our research labs work closely with MDA clinics and clinicians at UW and Seattle Children’s Hospitals (Wang), as well as with the Medical Centers affiliated with Project 2 at the Universities of Kansas (Statland), Nevada (Jones) and Rochester (Tawil). We also organize workshops to bring patients and their families to joint sessions with clinicians and researchers, increasing our outreach and providing a space for patients to educate and impact trainees on their perspectives and concerns. Overall, our plan is to foster an environment of communication, collaboration, and career development mentoring that encourages participation in muscular dystrophy research. This goal will be coupled with outreach and communications to families and by working with patient advocacy groups to disseminate research and clinical updates.