Resources and Workforce Development for the Regional Biocontainment Laboratories

摘要--总体 杜克大学很高兴对RFA-IP-22-075《有限竞争：资源和 区域生物遏制实验室的劳动力发展“。杜克大学是美国国立卫生研究院资助的12个 国家区域生物遏制实验室(RBL)，并在世界上发挥了仪器作用 在DHVI和整个杜克大学和研究中心进行的班级翻译研究 三角区，提供病毒学、免疫学、微生物学和动物模型服务的BSL-3套件。 这笔赠款的支助将加强整体基础设施、持续的设施和设备维护， 建立增强的BSL-3安全和培训计划，并加强对 位于BSL-3环境中的现有RBL研究支持服务。这件事的意义 格兰特表示，这将使公爵RBL更好地应对新出现的传染病，并发挥主导作用 在预防大流行方面的作用。这项建议的具体目标是1)保持可靠和不受干扰 设施功能；2)确保安全、可靠和合规的工作环境；以及3)提供- 加强NIAID生物防御的最先进的生物遏制研究环境和相关支持服务 设施网络。这笔赠款将继续使杜克大学成为一支内部和 致力于研究和对抗特定病原体和BSL-3/ABSL-3感染性病原体的外部调查人员 具有全球重要性。

ABSTRACT – Overall Duke University is pleased to respond to RFA-IP-22-075 entitled “Limited Competition: Resources and Workforce Development for the Regional Biocontainment Laboratories”. Duke is one of 12-NIH funded Regional Biocontainment Laboratories (RBLs) in the country and has played an instrument role in the world class translational research being conducted at the DHVI and others throughout Duke and the Research Triangle region, by providing BSL-3 suites for virology, immunology, microbiology, and animal model services. Support from this grant will strengthen the overall infrastructure, ongoing facility and equipment maintenance, establish an enhanced BSL-3 safety and training program, and enhance access to and capabilities of the existing RBL Research Support services that are located in the BSL-3 environment. The significance of this grant is that it will allow the Duke RBL to better respond to emerging infectious diseases and play a leading role in pandemic preparedness. Specific Aims for this proposal are 1) to maintain reliable and uninterrupted facility functionality; 2) to ensure a safe, secure, and compliant work environment; and 3) provide a state-of- the-art biocontainment research environment and related support services that enhance the NIAID Biodefense Facilities Network. This grant will continue to allow Duke to be a crucial resource to a team of internal and external investigators dedicated to studying and countering select agents and BSL-3/ABSL-3 infectious agents of global importance.