Relating laboratory measures of UE prosthesis performance to use in everyday life

描述（由申请人提供）： 研究建议：将UE假体性能的实验室测量与日常生活中的使用相关联：一项初步研究。主要研究者：亚历山大W. Dromerick，MD摘要我们的长期目标是通过改善他们接受的治疗来改善上肢截肢的退伍军人和平民的生活。在这个试点提案中，我们通过系统地评估假肢在日常生活中的使用来实现这一目标。我们将使用客观和自我报告的措施，并将这些真实的世界的措施，以常用的和实验室为基础的措施。这项工作将提供关于假肢日常使用的试验数据，以及它们与常用的实验室技能测量的关系。它还将客观地评估改善假体设计和训练的两个有希望的目标（躯干和残肢的补偿动作;握力控制）是否与现实世界的使用有关。如果是这样的话，这些可能是未来假肢设计和训练协议的目标。这些试点数据将为这些重要领域提供即时的初步见解，并将为更大规模的确定性研究奠定基础。我们的目标：具体目标1：检查日常假肢使用的主观报告和客观指标（手臂运动和终端设备激活）之间的关系。这些数据将用于估计后续更大规模确定性研究的效应量。具体目标二：检查实验室测量的粗和精细运动性能，躯干补偿，抓握运动控制与日常假肢使用的主观和客观措施之间的关系。 公共卫生相关性： 截肢者护理长期以来一直是为退伍军人提供护理的重要组成部分。拟定项目旨在比较UE假体使用的临床/实验室测量结果与“真实的世界”环境中实际使用的假肢。最近从军事剧院涌入的新UE截肢者强调了对优质护理的需求。更好地了解实验室测量与实际假肢使用之间的关系，将为VHA临床医生和政策制定者提供必要的工具，以便就新技术、培训技术和其他干预措施的益处和局限性做出合理决策。

DESCRIPTION (provided by applicant): Research Proposal: Relating laboratory measures of UE prosthesis performance to use in everyday life: A Pilot Study. Principal Investigator: Alexander W. Dromerick, MD Abstract Our long term objective is to improve the lives of veterans and civilians with upper extremity (UE) amputation by improving the treatments they receive. In this pilot proposal, we advance towards this goal by systematically evaluating use of prosthetic limbs in everyday life. We will use objective and self-report measures, and relate these real world measures to both commonly used and experimental laboratory-based measures. This work will provide pilot data about everyday use of prosthetic limbs and how they relate to commonly used laboratory measures of skill. It will also objectively evaluate whether two promising targets for improving prosthesis design and training (compensatory maneuvers of the trunk and residual limb; grip force control) are related to real-world use. If so, these could be targets for future prosthetic limb designs and training protocols. This pilot data will provide immediate preliminary insight into these important areas, and will form the basis for larger-scale definitive studies. Our Aims: Specific Aim 1: Examine the relationship between subjective reports and objective indicators of everyday prosthesis use (arm motion and terminal device activation). These data will be used to estimate effect size for a subsequent larger scale definitive study. Specific Aim 2: Examine the relationship between laboratory measures of gross and fine motor performance, trunk compensation, and grip motor control with subjective and objective measures of everyday prosthesis use. PUBLIC HEALTH RELEVANCE: Project Narrrative Amputee care has long been a significant component of the care offered to military veterans. The proposed project intends to compare clinical/laboratory measurement of UE prosthesis use and actual prosthetic arm use in the "real - world" setting. The recent influx of new UE amputees from military theater highlights the need for quality care. A better understanding of how laboratory measurements relate to actual prosthetic arm use will provide VHA clinicians and policy makers with the tools needed to make rationale decisions about the benefits and limitations of new technologies, training techniques, and other interventions.