Genomics Proteomics Core
Genomics Proteomics Core
批准号:
7675680
负责人:
RICHARD A SLAYDEN
金额:
$19.1万
依托单位国家:
美国
项目类别:
财政年份:
2009
资助国家:
美国
项目状态:
已结题
起止时间:
2009-05-01 至 2014-04-30
关键词:
ArtsBindingBioinformaticsCommunicable DiseasesComputer AssistedCore FacilityCustomData AnalysesDetectionDevelopmentDiagnosticDrug DesignEquipmentExperimental DesignsFacility AccessesFee-for-Service PlansGenomicsGoalsHuman ResourcesLaboratoriesLearningMolecularPriceProteomicsPublic HealthResearchResearch PersonnelResearch SupportResourcesRoleServicesTechnical ExpertiseTechnologyTherapeuticVaccine AdjuvantViralbasebiodefensecomputing resourcescostdesigndrug discoveryimmunoregulationinstrumentationmanmouse genomepathogenresearch studytool
中文摘要
落基山地区卓越中心的基因组学蛋白质组学核心(核心E)的目标
在生物防御(RMRCE)是提供后基因组资源和材料,提供访问国家的,
艺术后基因组仪器,并提供专家协助进行后基因组
实验和生物信息学,从而增加了研究人员的研究机会,
成本GP-Core通过生产全基因组小鼠和病原体DMA阵列来实现这一目标
和其他分子检测工具和平台,通过提供和维护后基因组
在BL-3实验室附近的集中设施中使用仪器,并通过进行实验
对于那些由于缺乏人力或其他原因无法进行实验的研究人员来说,
专业知识,并提供生物信息学资源,工作人员和支持。GP-Core还开发了
技术和定制平台,供研究人员进行重点或更先进的后基因组研究。
因此,GP-Core(1)为研究人员生产和开发后基因组资源,(2)提供
获得后基因组设备(3)提供基因组学、蛋白质组学和生物信息学援助,
技术专长,(4)提供生物信息学和计算机辅助药物设计(CADD)服务,
为RMRCE研究者提供先进的诊断和治疗药物发现、设计和开发。
该中心的各项活动共同支持对公众重要的传染病研究目标
通过提供后基因组研究所需的资源和设备,
协助实验设计,数据分析和其他生物信息学相关的分析,以及后基因组学
在收费服务的基础上提供服务。
核心E将支持所有三个RMRCE综合研究重点免疫调节,佐剂和
疫苗(IRF 1)、细菌治疗(IRF 2)和病毒治疗(IRF 3)。其资源将
RP 1.4、1.6、1.7、2.1、2.2、2.3、2.4、2.5、2.7和3.4使用
英文摘要
The goal of the Genomics Proteomics Core (Core E) of the Rocky Mountain Regional Center of Excellence
in Biodefense (RMRCE) is to provide post-genomic resources and materials, to provide access to state-ofthe-
art post-genomic instrumentation, and to provide expert assistance in performing post-genomic
experiments, and bioinformatics, resulting in enhanced research opportunities for investigators at reduced
costs. The GP-Core accomplishes this goal by producing whole genome mouse and pathogen DMA arrays
and other molecular detection tools and platforms, by providing and maintaining post-genomic
instrumentation in a centralized facility adjacent to the BL-3 laboratories, and by performing experimentation
for investigators who would otherwise not be able to perform experiments because of a lack of manpower or
expertise, and providing access to bioinformatics resources, staff, and support. The GP-Core also develops
technology and custom platforms for investigators for focused or more advanced post-genomic studies.
Accordingly, the GP-Core (1) produces and develops post-genomic resources for investigators, (2) provides
access to post-genomic equipment (3) provides genomics, proteomics, and bioinformatics assistance and
technical expertise, and (4) provides bioinformatics and Computer-Aided Drug Design (CADD) services to
advance diagnostic and therapeutic drug discovery, design, and development for RMRCE investigators.
Together, the activities of the GP-Core support research objectives on infectious diseases important to public
health by providing resources and equipment that are required for post-genomic studies, technical
assistance for experimental design, data analysis and other bioinformatics-related analyses, and postgenomic
services on a fee-for-services basis.
Core E will support all three of the RMRCE Integrated Research Foci on Immunomodulation, Adjuvants and
Vaccines (IRF 1), Bacterial Therapeutics (IRF 2), and Viral Therapeutics (IRF 3). Its resources will be
utilized by RPs 1.4, 1.6, 1.7, 2.1, 2.2, 2.3, 2.4, 2.5, 2.7 and 3.4
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Development of novel broad spectrum chemotherapeutics against priority pathogens
-
批准号:8261425
-
项目类别:
-
资助金额:$34.07万
-
财政年份:2011
-
负责人:RICHARD A SLAYDEN
-
依托单位:
Genomics Proteomics Core
-
批准号:8261440
-
项目类别:
-
资助金额:$19.68万
-
财政年份:2011
-
负责人:RICHARD A SLAYDEN
-
依托单位:
Development and Formulation of Broad Spectrum Antimicrobials for Biodefense
-
批准号:7932903
-
项目类别:
-
资助金额:$97.89万
-
财政年份:2009
-
负责人:RICHARD A SLAYDEN
-
依托单位:
Development and Formulation of Broad Spectrum Antimicrobials for Biodefense
-
批准号:7645264
-
项目类别:
-
资助金额:$97.92万
-
财政年份:2009
-
负责人:RICHARD A SLAYDEN
-
依托单位:
Development of novel broad spectrum chemotherapeutics against priority pathogens
-
批准号:7675625
-
项目类别:
-
资助金额:$33.27万
-
财政年份:2009
-
负责人:RICHARD A SLAYDEN
-
依托单位:
Development of Novel Chemotherapeutics Against F. tularensis
-
批准号:7688230
-
项目类别:
-
资助金额:$13.89万
-
财政年份:2008
-
负责人:RICHARD A SLAYDEN
-
依托单位:
Post Genomic Bioinformatic Core
-
批准号:7641045
-
项目类别:
-
资助金额:$16.79万
-
财政年份:2008
-
负责人:RICHARD A SLAYDEN
-
依托单位:
Post Genomic Bioinformatic Core
-
批准号:7126265
-
项目类别:
-
资助金额:$13.8万
-
财政年份:2005
-
负责人:RICHARD A SLAYDEN
-
依托单位:
Regulation of Cellular division in M. tuberculosis
-
批准号:6863722
-
项目类别:
-
资助金额:$21.47万
-
财政年份:2003
-
负责人:RICHARD A SLAYDEN
-
依托单位:
Regulation of Cellular division in M. tuberculosis
-
批准号:7017688
-
项目类别:
-
资助金额:$20.97万
-
财政年份:2003
-
负责人:RICHARD A SLAYDEN
-
依托单位:
Regulation of Cellular division in M. tuberculosis
-
批准号:6654269
-
项目类别:
-
资助金额:$25.1万
-
财政年份:2003
-
负责人:RICHARD A SLAYDEN
-
依托单位:
Regulation of Cellular division in M. tuberculosis
-
批准号:6700743
-
项目类别:
-
资助金额:$23.97万
-
财政年份:2003
-
负责人:RICHARD A SLAYDEN
-
依托单位:
Post Genomic Bioinformatic Core
-
批准号:7451030
-
项目类别:
-
资助金额:$18.43万
-
财政年份:--
-
负责人:RICHARD A SLAYDEN
-
依托单位:
Development of novel broad spectrum chemotherapeutics against priority pathogens
-
批准号:8070319
-
项目类别:
-
资助金额:$38.35万
-
财政年份:--
-
负责人:RICHARD A SLAYDEN
-
依托单位:
Genomics Proteomics Core
-
批准号:8070334
-
项目类别:
-
资助金额:$22.1万
-
财政年份:--
-
负责人:RICHARD A SLAYDEN
-
依托单位:
Development of novel broad spectrum chemotherapeutics against priority pathogens
-
批准号:8465799
-
项目类别:
-
资助金额:$34.9万
-
财政年份:--
-
负责人:RICHARD A SLAYDEN
-
依托单位:
Post Genomic Bioinformatic Core
-
批准号:7310314
-
项目类别:
-
资助金额:$13.7万
-
财政年份:--
-
负责人:RICHARD A SLAYDEN
-
依托单位:
Development of novel broad spectrum chemotherapeutics against priority pathogens
-
批准号:8375702
-
项目类别:
-
资助金额:$29.99万
-
财政年份:--
-
负责人:RICHARD A SLAYDEN
-
依托单位:
国内基金
海外基金
登录
查看更多内容
帽结合蛋白(cap binding protein)调控乙烯信号转导的分子机制
-
批准号:32170319
-
项目类别:面上项目
-
资助金额:58.00万元
-
批准年份:2021
-
负责人:董春海
-
依托单位:
帽结合蛋白(cap binding protein)调控乙烯信号转导的分子机制
-
批准号:--
-
项目类别:--
-
资助金额:58万元
-
批准年份:2021
-
负责人:董春海
-
依托单位:
ID1 (Inhibitor of DNA binding 1) 在口蹄疫病毒感染中作用机制的研究
-
批准号:31672538
-
项目类别:面上项目
-
资助金额:62.0万元
-
批准年份:2016
-
负责人:孙跃峰
-
依托单位:
番茄EIN3-binding F-box蛋白2超表达诱导单性结实和果实成熟异常的机制研究
-
批准号:31372080
-
项目类别:面上项目
-
资助金额:80.0万元
-
批准年份:2013
-
负责人:杨迎伍
-
依托单位:
P53 binding protein 1 调控乳腺癌进展转移及化疗敏感性的机制研究
-
批准号:81172529
-
项目类别:面上项目
-
资助金额:58.0万元
-
批准年份:2011
-
负责人:杨其峰
-
依托单位:
DBP(Vitamin D Binding Protein)在多发性硬化中的作用和相关机制的蛋白质组学研究
-
批准号:81070952
-
项目类别:面上项目
-
资助金额:35.0万元
-
批准年份:2010
-
负责人:刘师莲
-
依托单位:
研究EB1(End-Binding protein 1)的癌基因特性及作用机制
-
批准号:30672361
-
项目类别:面上项目
-
资助金额:24.0万元
-
批准年份:2006
-
负责人:徐宁志
-
依托单位: