Microbiology and Immunology Training for HIV and HIV-Related Research in Uganda (MITHU)

 描述(由申请者提供)：这项名为“乌干达艾滋病毒和艾滋病毒相关研究的微生物学和免疫学培训”(Mithu)的新培训计划建立在凯斯西储大学(CWRU)及其在Makerere大学(MU)和联合临床研究中心(JCRC)合作伙伴28年的培训记录的基础上。Mithu的重点是基础微生物学和免疫学方面的生物医学培训，以应用于艾滋病毒和艾滋病毒/艾滋病相关疾病的研究。该计划旨在满足乌干达同事确定的最基本的培训需求，长期目标是加强乌干达主要大学和医学院的生物医学研究能力。Mithu的具体目标是：1.通过支持CWRU在微生物学和免疫学方面的博士级别培训，加强乌干达在教职员工层面的生物医学研究能力，这些培训是由在MU完成硕士级别培训的有才华的乌干达年轻科学家进行的。2.加强乌干达生物医学研究生教育，支持慕尼黑大学健康科学学院生物医学学院的硕士水平培训。3.建立关于艾滋病毒及其并发症的区域专门知识，以乌干达--水资源研究中心研究合作的基础设施和正在进行的研究为基础。4.通过乌干达健康科学家协会(USHS)发展一种指导年轻和发展中的实验室科学家的文化。5.继续与联合儿童权利委员会和慕尼黑大学的实验室密切合作，为乌干达的免疫学和微生物学研究提供先进的设施，供培训和回国的受训人员使用。米图提出了一项全面的基础科学计划，强调培训，以应对乌干达艾滋病毒疫情带来的不断变化的情况。拟议的项目将平衡MU和CWRU之间的教育和培训经验，以及乌干达的硕士水平培训和美国的博士培训。我们将在乌干达开设一门关于艾滋病毒和艾滋病毒/艾滋病相关感染的课程，重点是基础科学和技术的最新创新。本课程将作为硕士课程的核心课程，由乌干达和CWRU的讲师团队授课，讲师具有基础和临床病毒学、艾滋病毒的发病机制和抗药性、艾滋病毒/艾滋病的并发症，特别是艾滋病毒/结核病，以及基础和临床免疫学方面的专业知识。随着乌干达年轻生物医学科学家队伍的壮大，将会有对乌干达导师的需求。Mithu将与USHS一起组织导师培训，USHS是由前乌干达CWRU学员组织的一个协会。Mithu的研究培训将建立在由NIH、CDC、B&MGF、EDTCP和其他机构资助的UCRC项目的基础设施和研究活动的基础上。他们为密歇根州立大学的硕士培训创造了良好的环境，并为CWRU的博士培训创造了生物医学假说。

 DESCRIPTION (provided by applicant): This new training program, entitled "Microbiology and Immunology Training for HIV and HIV-Related Research in Uganda" (MITHU) builds on the 28 year training record of Case Western Reserve University (CWRU) and partners at Makerere University (MU) and the Joint Clinical Research Center (JCRC). MITHU's focus is on biomedical training in basic microbiology and immunology to be applied to HIV and HIV/AIDS-related diseases research. The program has been designed to meet the most essential training needs identified by colleagues in Uganda with a long-term goal of strengthening the biomedical research capacity of major universities and medical schools in Uganda. MITHU's Specific Aims are: 1. To strengthen Ugandan biomedical research capacity at the faculty level by supporting PhD level training in microbiology and immunology at CWRU of talented young Ugandan scientists who have completed Master's level training at MU. 2. To strengthen graduate education in biomedical sciences in Uganda by supporting Master's level training in the School of Biomedical Sciences at MU's College of Health Sciences. 3. To establish regional expertise on HIV and its complications by building on the infrastructure and ongoing research of the Uganda-CWRU Research Collaboration (UCRC). 4. To develop a culture of mentoring young and developing laboratory scientists through the Uganda Society of Health Scientists (USHS). 5. To continue close collaborations between MITHU and laboratories at JCRC and MU to provide advanced facilities for immunology and microbiology research in Uganda for training and for returning trainees. MITHU proposes a comprehensive, basic science program emphasizing training that addresses the changing circumstances imposed by the HIV epidemic in Uganda. The proposed program will balance education and training experiences between MU and CWRU, with Master's level training in Uganda and PhD training in the US. We will offer a course in Uganda on HIV and HIV/AIDS-related infections focused on the latest innovations in basic science and technology. This course will serve as a Core Course for the Master's program and will be team-taught by lecturers in Uganda and CWRU with expertise in the basic and clinical virology, pathogenesis and drug resistance of HIV, complications of HIV/AIDS, particularly HIV/TB, and basic and clinical immunology. As the cadre of young biomedical scientists grows in Uganda, there will be a demand for Ugandan mentors. MITHU will organize mentor training with USHS, a society organized by former Ugandan CWRU trainees. Research training in MITHU will build on the infrastructure and research activities of UCRC projects funded by NIH, CDC, B&MGF, EDTCP, and others. They create a robust environment for Master's training at MU and generate biomedical hypotheses for PhD training at CWRU.