Cancer Prevention and Control

项目摘要 在美洲印第安人和阿拉斯加原住民中很少有癌症预防和控制或癌症病因学的研究(AI/ANS) 在美国，包括人工智能/人工智能作为调查人员。AI/ANS在癌症研究中的主要研究角色有 尤其不常见。尽管部落社区中许多由非人工智能/ANS进行的癌症控制研究 他们怀着降低癌症发病率和死亡率的良好意图进行，但往往无法实现 减少部落人口中与癌症有关的差距。这种缺乏进展在一定程度上与许多 在与AI/AN社区合作时遇到的挑战，包括缺乏信任，这可能需要许多 需要数年时间才能确立。在癌症控制项目中扮演关键角色的人工智能/人工智能调查人员显然需要更有效地 解决人工智能/人工智能社区的癌症负担，包括基于保留的社区和城市社区。 该项目的基本原理是，训练有素的人工智能/人工智能研究人员将具有文化能力，并将被视为 将参与研究项目或受其影响的社区成员值得信赖和可信的研究人员 由此计划中的AI/AN参与者实施。学员不仅可能工作和生活在他们的 各自的社区，但他们比非人工智能/人工智能更有可能懂土著语言，而且更 有动力长期留在他们的社区。在我们早先在这方面取得成功的基础上，我们的目标是： 1)招聘和保留40名合格的人工智能/人工智能/人工智能研究人员，他们寻求在癌症控制研究和 实施癌症控制项目； 2)设计并提供为期三周的量身定做的癌症控制研究课程，使用经验丰富的合格教师 和顾问，为每个受训者带来一个顶峰癌症预防研究项目； 3)为学员提供后续支持，包括现场支持、远程学习机会和指导 在完成癌症控制研究的正式课程后；以及 4)为完成为期三周课程的有兴趣的学员提供癌症控制研究实习机会，以便 在密切的指导下，他们可以掌握与社区癌症控制职业相关的额外研究技能。 影响：我们早期的努力，虽然在我们的研究生实习生中取得了可衡量的成功，但只是不够的。我们 需要对训练有素的人工智能/癌症控制研究人员进行更大的联邦投资，这些研究人员可以为研究带来科学严谨 他们将在人工智能/人工智能人群中设计和实施，以提高癌症发病率和风险。

Project Summary Few studies of cancer prevention and control or of cancer etiology among American Indians and Alaska Natives (AI/ANs) in the US have included AI/AN people as investigators. AI/ANs in Principal Investigator roles in cancer research have been particularly uncommon. Although many cancer control studies by non-AI/ANs in tribal communities have been conducted with good intentions toward reduction of cancer incidence and mortality, they have often failed to achieve a reduction in cancer-related disparities among tribal populations. This lack of progress is partly related to the many challenges that 'outsiders' experience in working with AI/AN communities, including the lack of trust that may take many years to establish. AI/AN investigators in key roles in cancer control projects are clearly needed to more effectively address the cancer burden in AI/AN communities, both reservation-based and urban. The rationale for the project is that well-trained AI/AN researchers will have cultural competency and will be viewed as trustworthy and credible researchers by community members who will participate in, or be affected by, research projects implemented by the AI/AN participants in this program. Not only are the trainees likely to be working and living in their respective communities, but they are more likely than non-AI/ANs to know the indigenous language and are more motivated to stay in their communities long-term. Building on our earlier success in this area, our aims are: 1) to recruit and retain 40 qualified AI/AN researchers who seek additional training in cancer control research and in the implementation of cancer control projects; 2) to design and offer a tailored three-week cancer control research curriculum using experienced and qualified faculty and consultants, leading to a capstone cancer prevention research project for each trainee; 3) to provide follow-up support, including field support, distance learning opportunities, and mentoring to the trainees after they complete the formal curriculum in cancer control research; and 4) to provide cancer control research internships to interested trainees who complete the three-week curriculum, so that they can master additional research skills relevant to careers in community-based cancer control under close mentorship. Impact: Our earlier efforts, while showing measureable success among our graduate trainees, are simply not enough. We need a larger federal investment in well trained AI/AN cancer control researchers who can bring scientific rigor to studies they will design and implement in AI/AN populations, to improve cancer rates and risks.