Career Enhancement Program

项目摘要 马约诊所乳腺癌SPORE的职业提升计划（CEP）致力于识别 指导最有潜力开发翻译独立项目的初级教师 乳腺癌研究。这是通过严格的审查过程来实现的，目的是确定 有才华和有前途的候选人，其次是密集，严格和有效的指导计划。的 指导计划是建立在多学科指导的建立和最佳运作的基础上 委员会由一名具有科学专业知识的高级研究员领导，致力于开发下一个 转化型乳腺癌研究人员的一代。多学科指导委员会将 由主要导师和辅助临床和/或基础研究者组成， 全面的指导计划加上一名统计员。它被认为是至关重要的获奖者的成功， 辅导工作应持续进行，并保持活力。这将在选委会主任的密切监督下完成 的辅导过程和获奖者的进展。CEP主任将向SPORE Co报告， 董事向SPORE执行委员会汇报。这一密集的监督过程是 由于SPORE联席董事坚信独立发展 研究人员和转化乳腺癌研究是核心的孢子使命。显式 期望获奖者将利用提供给他们的资源， 独立的研究项目和获得乳腺癌研究的独立资金。我们 每年需要5万美元（直接费用）来支持该计划。这将由50 000美元补充 马约诊所癌症中心支持的直接成本。每年将颁发10万美元的奖金， 用于支付工资、技术支持和供应。每年将资助一名获奖者， 如有令人满意的进展，获奖者可获得长达两年的支持。迄今 CEP的成功之处在于，三名CEP获奖者都是高效的，并成功地 竞争成为SPORE完整项目的项目共同领导人。

Project Summary The Career Enhancement Program (CEP) of the Mayo Clinic Breast Cancer SPORE is committed to identifying and mentoring junior faculty with the greatest potential of developing independent programs in translational breast cancer research. This is accomplished through a rigorous review process aimed at identifying the most talented and promising candidates followed by an intensive, rigorous and effective mentoring program. The mentoring program is based on the establishment and optimal functioning of a Multidisciplinary Mentoring Committee led by a senior investigator with the scientific expertise and commitment to developing the next generation of translational breast cancer researchers. The Multidisciplinary Mentoring Committee will be composed of the primary mentor and the complementary clinical and/or basic investigator necessary for a comprehensive mentoring program plus a statistician. It is viewed as crucial to the success of the awardee that the mentoring be ongoing and robust. This will be accomplished by close oversight by the Director of the CEP of the mentoring process and progress of the awardee. The Director of the CEP will report to the SPORE Co- Directors who, in turn, report to the SPORE Executive Committee. This intensive oversight process was established because of the firm conviction of the SPORE Co-Directors that the development of independent investigators and translational breast cancer research is central to the SPORE mission. The explicit expectation is that the awardees will utilize the resources made available to them for the development of independent research programs and acquisition of independent funding in breast cancer research. We are requesting $50,000 per year (direct costs) to support this program. This will be supplemented by $50,000 (direct costs) of Mayo Clinic Cancer Center support. One award of $100,000 per year will be made, which can be used for salary, technician support, and supplies. One awardee will be supported per year and a given awardee can be supported for up to two years providing satisfactory progress is demonstrated. To date the CEP has been successful in that three CEP awardees have been highly productive and have successfully competed to become Project Co-Leaders in full Projects of the SPORE.