A Wearable Electrochemical Alcohol Sensor

项目总结/摘要 测量酒精消费量对个人健康和预防不良反应非常重要。 喝酒的后果。对可穿戴的酒精连续感测有巨大的需求 准确、微创或无创、无阻塞且价格合理的设备。然而，在这方面， 现有技术不能提供具有可穿戴设备所需的所有规格的酒精传感器。 设备，包括尺寸，功率，灵敏度，特异性，安全性，可制造性和成本。的 建议的项目是开发一种酒精传感器，通过创新适用于可穿戴应用 电化学酒精传感器这项创新利用微制造技术， 灵敏度高、安全性高、可制造性好、成本低， 结构所设计的电解质-电极界面的催化效果达到了很高的 灵敏度高、选择性好。传感器的尺寸小于2x2毫米，可以解锁 可穿戴设备、智能手机和汽车用于呼吸中的酒精检测的许多可能性， 间质液或血液。在这个项目中，我们的目标是通过一个例子来展示这项技术。 可准确且连续监测的环形形状因子无线供电可穿戴设备 体液中的酒精含量在第一阶段，除了酒精传感器， 生物相容性微针阵列被设计成无痛地采样和输送组织间液 到传感器。微针阵列被设计成沿着在微针阵列上的传感器一起被处理。 相同的硅衬底。整个过程与互补的半导体器件的制造兼容。 氧化物金属半导体（CMOS），允许进一步单片集成的微针 阵列，酒精传感器，和CMOS传感器读出集成电路（IC）在第二阶段。

Project Summary/Abstract Measuring alcohol consumption is important to individual health and the prevention of adverse consequences of drinking. There are tremendous needs for wearable alcohol continuous sensing devices that are accurate, minimal- or non-invasive, unobstructive and affordable. However, existing technologies cannot provide alcohol sensors with all specifications desired by wearable devices, including size, power, sensitivity, specificity, safety, manufacturability and cost. The proposed project is to develop an alcohol sensor suitable for wearable applications by innovating electrochemical alcohol sensors. The innovation uses microfabrication techniques to achieve high sensitivity, high safety, good manufacturability and low cost with a miniaturized membraneless structure. The catalytic effect of the designed electrolyte-electrode interface achieves high sensitivity and high selectivity. The size of the sensor is less than 2x2 millimeters, can unlock many possibilities for wearable, smartphone, and automobile for alcohol detection in breath, interstitial fluid, or blood. In this project, we aim to demonstrate the technology by an examplary ring form factor wireless powered wearable device that can accurately and continuously monitor the alcohol level in body fluid. In Phase I, in addition to the alcohol sensor, a minimal invasive biocompatible microneedle array is designed to painlessly sample and deliver the interstitial fluid to the sensor. The microneedle array is designed to be processed along with the sensor on the same silicon substrate. The entire process is compatible with the fabrication of complimentary oxde metal semiconductor (CMOS), allowing the further monolithic integration of the microneedle array, the alcohol sensor, and the CMOS sensor readout integrated circuit (IC) in Phase II.