Prototype Construction Core

项目概要-原型施工核心（PCC） NEI赞助的斯坦眼科研究所（SEI）的研究人员的研究呼吁开发 和改进创新的光谱学、电生理学、光学和机械系统。到 支持这一需求，一个国家的最先进的计算机数控（CNC）制造和工程 该设施已在SEI中建立。该设施使得能够构造新颖的装置， 这些工具引导NEI调查人员进入未探索和令人兴奋的研究领域。响应于 审查者在上次审查中的评论对我们的模块结构作了修改。上一 创新技术模块还包括生物化学和光谱学设备 作为原型制造（机械车间）。两者都有非常沉重的使用，并指出， 审查人员很容易被分开。因此，原型构建核心（PCC）模块具有 作为一个独立的核心被剥离出来，仍然是订阅量最大的。创新变革 在PCC模块中，建议的更新包括： A.人员改进，包括一名受过正式培训的CNC机械师， 电子学学位。 B。采购和更新最先进的制造设备。 C.改善访问和可用性。扩大校园内NEI助学金持有者的访问权限 需要独特的原型进行实验。 D.培训（针对在计算机辅助设计和制造方面缺乏经验的人员）。 E.项目优先级，以提高制造效率，确定项目紧迫性 F.核心组件的协同使用。 G.促进合作关系，特别是临床和基础研究 我们将在研究策略中详细讨论拟议和最近实施的变更。

PROJECT SUMMARY - PROTOTYPE CONSTRUCTION CORE (PCC) The NEI sponsored research of investigators at the Stein Eye Institute (SEI) calls for the development and modification of innovative spectroscopic, electrophysiological, optical and mechanical systems. To support this need, a state-of-the-art computer numerical controlled (CNC) fabrication and engineering facility has been established at the SEI. This facility enables the construction of novel devices and instruments that lead NEI investigators into unexplored and exciting areas of research. In response to reviewers comments in the last review changes were made in our modular structure. In the previous cycle the Innovative Technology module included Biochemistry and Spectroscopy equipment as well as prototype fabrication (machine shop). Both had extremely heavy usage and as indicated by the reviewers could easily be separated. Therefore, the Prototype Construction Core (PCC) Module has been spun off as a separate core and is still one of the most heavily subscribed. Innovative changes have been made in the PCC module which in the proposed renewal include: A. Personnel improvements including a formally trained CNC mechanician with a secondary degree in electronics. B. Acquisition and updating of state of the art fabrication equipment. C. Improved Access and Availability. To extend access to NEI grant holders on the campus with need for unique prototypes for experimentation. D. Training (for personnel with little experience in computer aided design and fabrication). E. Project Prioritization to streamline efficiency in fabrication, determine project urgency F. Synergistic Use of the Core Components. G. Foster Collaborative Relationships, Particularly Clinical and Basic Research The proposed and recently implemented changes will be discussed in detail in our Research Strategy.