Research Support Core

摘要-研究支持核心 此核心支持中心补助金（P30）申请要求继续支持分析化学 实验室和行政部门共用核心基础设施，并为试点项目核心提供支助。的总体目标 研究支持中心的任务是提供最先进的、装备精良的和配备人员的实验室资源， 加州大学旧金山分校和其他机构的药物滥用研究人员的参与项目。我们的合作者 需要复杂的分析化学来测量毒品的浓度， 代谢物和生物标志物，以便进行研究。目标是提供支持， 随着组成科学项目的变化和发展，对这些项目的需求作出反应。为研究 随着优先事项的变化和新的发现，尖端研究需要开发新的 方法.我们的实验室在分析方法和生物标志物开发方面有多年的经验， 配备了最先进的仪器和经验丰富的工作人员。开发所需的新方法 未来的合作研究是由我们的P30中心支持的一项主要活动。这个设施是一个成本- 有效的共享实验室资源，增强和扩展研究人员的研究可能性， 由NIH或其他联邦或非联邦来源资助，以进一步了解人类精神活性药物 使用、滥用和成瘾，其健康后果及其治疗管理。

ABSTRACT – RESEARCH SUPPORT CORE This Core Support Center Grant (P30) application requests continued support for an analytical chemistry laboratory and administrative shared core infrastructure, and support for a pilot project core. The overall aim of the Research Support Core is to provide a state-of-the-art, well equipped and staffed laboratory resource for the participating projects of drug abuse researchers at UCSF and at other institutions. Our collaborators throughout the country require sophisticated analytical chemistry to measure concentrations of drugs, their metabolites, and biomarkers in order to carry out their research. The objective is to provide support that is responsive to the needs of constituent scientific projects, as these projects change and evolve. As research priorities change and new discoveries are made, cutting-edge research requires the development of new methods. Our laboratory has many years experience in analytical method and biomarker development, is equipped with state-of-the-art instruments, and a very experienced staff. Developing new methods required for future collaborative research is a major activity that is supported by our P30 Center. This facility is a cost- effective shared laboratory resource that enhances and extends research possibilities of investigators currently funded by NIH or other federal or nonfederal sources to further our understanding of human psychoactive drug use, abuse and addiction, its health consequences and its treatment management.