Assay Guidance Manual
Assay Guidance Manual
批准号:
10011458
负责人:
Anton Simeonov
金额:
$3.37万
依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
未结题
起止时间:
至
关键词:
AcademiaAddressArrestinsAutomationBiologicalBiological AssayCell CommunicationCellsChemicalsCollectionCoupledCyclic AMPDataDevelopmentDisciplineEnzymesFluorescenceGenomicsGoalsGovernmentGuidelinesImmunoassayIndustrializationIndustryInvestigationLaboratory ResearchLuciferasesManualsMeasurementMeasuresMethodsMolecularMorphologic artifactsPathway interactionsPerformancePharmaceutical PreparationsPharmacologic SubstancePhenotypeProtein InhibitionProteinsProtocols documentationReagentReporterReportingResearch PersonnelResourcesScientistScreening ResultSignal TransductionSmall Interfering RNASourceStructure-Activity RelationshipTherapeuticTranslational ResearchUpdateValidationassay developmentbasecytotoxicitydrug developmentdrug discoveryelectronic bookengineered nucleasesexperiencegenome editinghigh throughput screeninghistone acetyltransferasein vitro Assayin vivoinstrumentationprotein protein interactionreceptorreceptor bindingrecruitscreening
中文摘要
新篇章
细胞毒性试验:测量死细胞的体外方法2019年5月1日
Gs和Gi蛋白偶联受体(GPCR)的cAMP测量2017年11月20日
GPCR靶标的-抑制蛋白募集的测量2017年11月20日
使用工程核酸酶进行基因组编辑及其在基因组筛选中的应用2017年11月20日
蛋白质-蛋白质相互作用的抑制:基于细胞的试验2017年11月20日
最近更新的章节
免疫测定方法2019年7月8日
HTS和药物发现的受体结合试验2018年7月1日
药物和化学探针发现中的组蛋白乙酰转移酶测定01 Jul 2018
干扰荧光和吸光度2018年7月1日
干扰荧光素酶报告酶2018年7月1日
英文摘要
New Chapters
Cytotoxicity Assays: In Vitro Methods to Measure Dead Cells 01 May 2019
Measurement of cAMP for Gs- and Gi Protein-Coupled Receptors (GPCRs) 20 Nov 2017
Measurement of -Arrestin Recruitment for GPCR Targets 20 Nov 2017
Genome Editing Using Engineered Nucleases and Their Use in Genomic Screening 20 Nov 2017
Inhibition of Protein-Protein Interactions: Cell-Based Assays 20 Nov 2017
Recently Updated Chapters
Immunoassay Methods 08 Jul 2019
Receptor Binding Assays for HTS and Drug Discovery 01 Jul 2018
Histone Acetyltransferase Assays in Drug and Chemical Probe Discovery 01 Jul 2018
Interference with Fluorescence and Absorbance 01 Jul 2018
Interferences with Luciferase Reporter Enzymes 01 Jul 2018
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
A Novel Compound for Targeted Treatment of CBF Leukemia
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批准号:9205569
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项目类别:
-
资助金额:$200.38万
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财政年份:--
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负责人:Anton Simeonov
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依托单位:
Profliing Assay for Redox Potential
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批准号:9772066
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项目类别:
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资助金额:$4.08万
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财政年份:--
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负责人:Anton Simeonov
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依托单位:
Identification of Myc translation inhibitors
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批准号:9554527
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项目类别:
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资助金额:$4.47万
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财政年份:--
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负责人:Anton Simeonov
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依托单位:
Trans-NIH RNAi Facility (TNRF)
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批准号:9205806
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项目类别:
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资助金额:$47.5万
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财政年份:--
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负责人:Anton Simeonov
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依托单位:
Identification of Grb10:Insulin Receptor Disruptors
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批准号:9554524
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项目类别:
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资助金额:$4.47万
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财政年份:--
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负责人:Anton Simeonov
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依托单位:
PRKACA for Fibrolamellar hepatocellular carcinoma
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批准号:9554490
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项目类别:
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资助金额:$4.47万
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财政年份:--
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负责人:Anton Simeonov
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依托单位:
MST/ITC studies on Vimentin DHA interaction
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批准号:9554499
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项目类别:
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资助金额:$4.47万
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财政年份:--
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负责人:Anton Simeonov
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依托单位:
Disrupting Type IV secretion function to prevent virulence in the pathogenic bacterium Legionella pneumophila
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批准号:9554502
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项目类别:
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资助金额:$13.57万
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财政年份:--
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负责人:Anton Simeonov
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依托单位:
A Novel Compound for Targeted Treatment of CBF Leukemia
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批准号:9550575
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项目类别:
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资助金额:$205.31万
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财政年份:--
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负责人:Anton Simeonov
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依托单位:
Protein Kinase CAMP-Activated Catalytic Subunit Alpha
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批准号:9554489
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项目类别:
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资助金额:$4.47万
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财政年份:--
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负责人:Anton Simeonov
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依托单位:
High-throughput multiparametric drug screening method for 3D spheroids
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批准号:9554522
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项目类别:
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资助金额:$4.47万
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财政年份:--
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负责人:Anton Simeonov
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依托单位:
Functional Genomics Laboratory (FGL)
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批准号:10682312
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项目类别:
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资助金额:$107.78万
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财政年份:--
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负责人:Anton Simeonov
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依托单位:
15-hLO-1 inhibitors as Potential Therapeutics Against Stroke
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批准号:10011389
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项目类别:
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资助金额:$13.27万
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财政年份:--
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负责人:Anton Simeonov
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依托单位:
Screening to identify potent and specific inhibitors of N-terminal methyltransferase (NTMT1) as chemical probes
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批准号:10011397
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项目类别:
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资助金额:$13.27万
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财政年份:--
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负责人:Anton Simeonov
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依托单位:
Identification of small molecule inhibitors of USP8
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批准号:10011437
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项目类别:
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资助金额:$4.76万
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财政年份:--
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负责人:Anton Simeonov
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依托单位:
Identification of inhibitors of Zika Protease (NS2B-NS3)
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批准号:10005788
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项目类别:
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资助金额:$13.27万
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财政年份:--
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负责人:Anton Simeonov
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依托单位:
Activation-induced cytidine deaminase
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批准号:10011394
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项目类别:
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资助金额:$25.03万
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财政年份:--
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负责人:Anton Simeonov
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依托单位:
qHTS to Identify Inhibitors of Rabies Virus
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批准号:10011405
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项目类别:
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资助金额:$13.27万
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财政年份:--
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负责人:Anton Simeonov
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依托单位:
Aminoadipate semialdehyde synthase as a therapeutic target for pyridoxine dependent epilepsy
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批准号:10269700
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项目类别:
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资助金额:$11.24万
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财政年份:--
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负责人:Anton Simeonov
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依托单位:
Disrupting Type IV secretion function to prevent virulence in the pathogenic bacterium Legionella pneumophila
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批准号:10269713
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项目类别:
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资助金额:$18.66万
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财政年份:--
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负责人:Anton Simeonov
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依托单位:
海外基金