Developmental Research Program

项目摘要 纽约大学癌症健康差异（CHD）孢子发育研究计划（DRP）的总体目标 是刺激新的转化研究，以减少少数民族之间的口腔消化（ODT）癌症差异， 低收入人群。纽约大学CHD SPORE DRP的目标是：1）为有前途的研究提供资金 在癌症的健康差距在口腔消化道癌症，因为它涉及到的相互作用的微生物和免疫 2）寻求支持在ODT癌症中开展“高风险，高回报”的研究; 3）吸引 研究人员用新的方法来解决导致口腔消化道癌症健康差异的问题 癌症;以及4）监测发展研究项目的进展。该计划将促进 通过资助试点项目，探索翻译ODT癌症差异研究的创新思路 助理教授或更高级别的研究人员。DRP将提供指导、建议、评估， 资助5-7个试点项目。具体而言，DRP每年将支持至少两个试点项目，每个项目 12-一个月的期限，并可选择竞争性续约12个月。每个试点项目的目标 是产生足够的高质量数据，以推进对ODT癌症的研究， 向NIH或其他联邦机构提交一个引人注目的独立项目以获得资助。我们将鼓励 DRP项目链接到正在进行的纽约大学CHD SPORE项目。DRP的联合主任是乔治博士 米勒和Chau Trinh-Shevrin博士。米勒博士是外科和细胞生物学教授，也是Perlmutter的领导者。 综合癌症中心（PCC）肿瘤免疫学项目。Chau Trinh-Shevrin博士是助理 人口健康教授和社区外展和参与PCC的副主任。

PROJECT SUMMARY The overall goal of the NYU Cancer Health Disparity (CHD) SPORE Developmental Research Program (DRP) is to stimulate novel translational research to reduce orodigestive (ODT) cancer disparities among minority and low-income populations. The aims of the NYU CHD SPORE DRP are to: 1) provide funds for promising research in cancer health disparities in orodigestive cancers as it relates to the interplay of the microbiome and immune response; 2) seek to support the development of “high-risk, high-reward” investigations in ODT cancers; 3) attract investigators with novel approaches to solving issues that contribute to cancer health disparity in orodigestive cancers; and 4) monitor the progress of developmental research projects. This program will promote the exploration of innovative ideas in translational ODT cancer disparities research by funding pilot projects proposed by investigators at the Assistant Professor level or higher. The DRP will provide guidance, advice, evaluation, and funding for 5–7 pilot projects. Specifically, the DRP will support at least 2 pilot projects per year, each for a 12-month period, with the option of a competitive renewal for another 12 months. The goal for each pilot project is to generate sufficient high-quality data to advance investigation of ODT cancers to the extent that it will enable submission of a compelling independent project to the NIH or other federal agency for funding. We will encourage DRP projects that link to an ongoing NYU CHD SPORE project. The co-Directors of the DRP are Dr. George Miller and Dr. Chau Trinh-Shevrin. Dr. Miller is Professor of Surgery and Cell Biology and leader of the Perlmutter Comprehensive Cancer Center (PCC) Tumor Immunology Program. Dr. Chau Trinh-Shevrin is Associate Professor of Population Health and Associate Director for Community Outreach and Engagement in the PCC.