14th International Conference on HIV Treatment, Pathogenesis, and Prevention Research (INTEREST)

抽象的。 联合国艾滋病规划署对全球艾滋病毒负担的最新估计是， 全世界艾滋病毒1型感染者中有69.4%居住在撒哈拉以南非洲。明显，三 在撒哈拉以南非洲的四个新感染病例中， 15-24岁的人感染艾滋病毒的可能性是同龄男子的两倍。此外， 在撒哈拉以南非洲的东部/南部和西部/中部地区之间存在着一种趋势， 自2010年以来，艾滋病相关死亡率分别为42%和24%。显然，在以下方面仍有许多工作要做： 培训当地医生和科学家诊断，治疗和管理个人与 艾滋病毒-1感染;进行科学的执行工作，以确定最具成本效益的资金使用方式 确保循证公共卫生政策和方案拟订， 非洲各次区域艾滋病应对措施存在差异。尽管治疗可能导致了 尽管艾滋病毒的传播速度有所减缓，但艾滋病毒预防仍然是遏制艾滋病毒浪潮的关键。事实上， 预计未来12年艾滋病将大流行，原因是：1）非洲人口结构的变化， 青年人数增加，2）传播的病毒耐药性增加，3）成本增加， 二线和三线治疗方案的可用性有限。综上所述，这些因素表明， 艾滋病患者总数每年可能增加200万人，达到惊人的5 000万人 到2030年全球 自2007年以来，13个成功的年度兴趣会议，被称为“非洲CROI”， 汇集了艾滋病诊断和治疗、发病机制和预防方面的科学家， 在非洲资源有限的环境中开展研究，以分享关键发现，促进合作， 在多个领域和多个大陆交流经验。2020年的规划和组织 本次会议将由阿姆斯特丹全球健康与发展研究所（Amsterdam Institute of Global Health and Development）主办。 Catherine Hankins博士是Interest国际会议委员会（ICC）的主席， 感兴趣的科学椅子。 2020年国际兴趣会议的组织者将追求以下目标： 1)提供诊断和治疗，发病机制， 预防艾滋病毒-1的成年人，包括老年人;青少年;和 非洲的艾滋病毒，以促进实现90-90-90病毒抑制目标， 防止第二次大规模流行病 2)促进主要研究者和代表研究者的人之间新的研究互动。 非洲大陆未来潜在的医疗保健和研究科学领导者。

Abstract. The most recent UNAIDS estimates of the global burden of HIV are that 36.9 million people are living with HIV-1 infection worldwide, with 69.4% of these residing in sub-Saharan Africa. Markedly, three in four new infections in sub-Saharan Africa are among girls aged 15–19 years and young women aged 15–24 years are twice as likely to be living with HIV than men that age. Further, a striking difference exists between the east/southern and the west/central regions of sub-Saharan Africa, with reductions in AIDS-related deaths since 2010 of 42% and 24%, respectively. Clearly, much work remains in terms of training local physicians and scientists in the diagnosis, treatment, and management of individuals with HIV-1 infection; conducting implementation science to determine the most cost-effective use of financial and human resources; and ensuring evidence-informed public health policy and programming to reduce disparities in the AIDS response across Africa’s sub-regions. Despite treatment likely having contributed to slowing HIV transmission, HIV prevention remains critical to stem the tide of HIV. In fact, a second AIDS pandemic in the next 12 years is predicted due to 1) changing demographics in Africa with increasing numbers of youth, 2) increasing transmitted viral drug resistance, and 3) increased cost and limited availability of 2nd and 3rd line treatment regimens. Taken together, these factors suggest that the total number of people living with AIDS may increase by 2 million/year to reach a staggering 50 million worldwide by 2030. Since 2007, 13 successful annual INTEREST Conferences, known as the ‘African CROI’, have brought together scientists involved in HIV diagnosis and treatment, pathogenesis, and prevention research in resource-limited settings in Africa to share pivotal findings, promote collaboration, and transfer experiences across several fields and many continents. Planning and organization of the 2020 INTEREST Conference will be overseen by the Amsterdam Institute of Global Health and Development. Catherine Hankins MD PhD chairs INTEREST’s International Conference Committee (ICC) and is the Scientific Chair of INTEREST. The organizers of the 2020 INTEREST Conference will pursue the following objectives: 1) To provide cutting-edge knowledge in the fields of diagnosis and treatment, pathogenesis, and prevention of HIV-1 for adults, including the elderly; adolescents; and children living with HIV in Africa, in order to contribute to achieving the 90-90-90 viral suppression goal and to preventing a second great pandemic. 2) To foster new research interactions among leading investigators and those who represent the potential future scientific leadership for health care and research on the African continent.