Graduate Training in Cellular and Molecular Pathogenesis of Human Diseases

描述（由申请人提供）：细胞和分子病理学（CMP）研究生培训计划是威斯康星大学麦迪逊分校研究生院，病理科和医学与公共卫生学院（SMPH）的合资企业。该项目吸引了来自西澳大学研究生院和医学院20个部门的54名培训师，涵盖3个独立学院（医学、兽医医学和文理学院）。CMP的目标是为博士前培训创造一个刺激和强大的智力跨学科环境，融入一个令人兴奋和具有挑战性的基础和临床转化研究。CMP包括基础研究科学家和临床医生的积极参与，重点是了解主要人类疾病的发病机制和发展将生物学知识推向临床应用所需的技能。该项目有28名博士和26名博士或博士/博士资助的教师。我们申请资金用于培养2名1年级的博士预科生和2、3、4、5年级的博士预科生。将根据提名CMP培训师的建议、研究经验、推荐信以及增强多样性和为我国健康相关研究需求做出重大贡献的潜力，选择高素质的候选人。受训人员可获资助不超过3年。我们的课程提供现代病理生物学基本概念的跨学科和综合培训，重点是生化，细胞和分子方法以及对疾病基本基础的理解的严格深入的研究培训。我们让会员参与病理生物学教学课程和转化临床活动。我们提供癌症、神经系统和免疫系统疾病病理生物学方面的深入研究培训。CMP还帮助学生发展教学和领导技能。公众日益要求加强对研究支出的问责制，并且需要将基础科学的进步转化为临床应用，因此需要将医学培训进一步纳入研究生教育。我们的学员将具备病理生物学的基础知识和深入的研究经验，并结合对转化临床研究的理解。

DESCRIPTION (provided by applicant): The Cellular and Molecular Pathology (CMP) Graduate Training Program is a joint venture of the UW-Madison Graduate School, the Department of Pathology and the School of Medicine and Public Health (SMPH). The Program draws 54 trainers from 20 departments across the UW graduate campus and Medical School, spanning 3 separate colleges (Medicine, Veterinary Medicine and Letters & Science). The goal of the CMP is to create a stimulating and robust intellectual interdisciplinary environment for predoctoral training embedded in an exciting and challenging basic and clinical translational research. CMP includes the active participation of basic research scientists and clinicians with a focus on understanding the pathogenesis of major human diseases and developing skills needed to move biological knowledge toward clinical application. The program has 28 PhD and 26 MD or MD/PhD funded faculty. We are requesting funds for training 2 predoctoral students in Year 1 and 4 in Years 2,3,4 and 5. Highly qualified candidates will be selected based on the recommendation of nominating CMP trainer, research experiences, letters of recommendation and potential to enhance diversity and make significant contributions toward the health-related research needs of our nation. Trainees will be supported by the training grant for no longer than 3 years. Our curriculum provides interdisciplinary and integrated training in fundamental concepts in modern pathobiology with an emphasis on biochemical, cellular and molecular approaches and rigorous in-depth research training in understanding of the fundamental bases of diseases. We engage our members in didactic pathobiology courses and translational clinical activities. We provide in-depth research training in the pathobiology of cancer, nervous system and immune system diseases. CMP also helps students to develop teaching and leadership skills. Increasing public demand for greater accountability for research expenditures and the need for converting basic science advances into clinical applications call for higher integration of medical training into graduate education. Our trainees will have fundamental knowledge and in-depth research experience in pathobiology combined with understanding of translational clinical research. RELEVANCE: The primary objective of the CMP Graduate Program is to prepare our graduates for productive careers in scientific research and education and to position them to make significant contributions toward the health-related research needs of our nation.