Vision Research Core at UCLA

整体核心组件 项目摘要 加州大学洛杉矶分校的视觉研究有着悠久而丰富的历史，可以追溯到50多年前。的目的 加州大学洛杉矶分校视觉研究的核心拨款是提供一个急需的基础设施，以支持 这群有才华的科学家的共同目标是增加基本知识， 视觉系统及其紊乱为实现这一目标， 根据以下组成部分组织：（1）显微镜和图像分析，（2）实时成像， 功能评估，（3）生物化学和分子生物学仪器，（4）原型构建， (5)基因和细胞递送，和（6）软件工程。这些组件提供仪器， 多个实验室常用的技能，也是正在进行的项目取得成功的关键 以实现新的合作努力。它们为各种视觉科学家提供了切实的支持， 他们目前得到27个活跃的NEI R 01赠款的支持，加上额外的NEI资金。购买国家- 核心组成部分中的最先进的工具已经成为可能， 支持，其中，在许多情况下，杠杆校外支持，使购买有效。这 在未来五年内，我们会继续慷慨捐助。要求以核心赠款的形式提供支助， 通过服务合同维护这些仪器，并提供必要的人员支持， 并培训核心实验室成员使用核心设施。

Overall Core Component Project Summary Vision Research at UCLA has a long and rich history, dating back more than 50 years. The objective of the Core Grant for Vision Research at UCLA is to provide a critically needed infrastructure to support the research activities of this talented group of scientists whose common goal is to increase basic knowledge of the visual system and its disorders. To achieve this objective, personnel and instrument support facilities are organized according to the following components: (1) Microscopy and Image Analysis, (2) Live imaging and Functional Evaluation, (3) Biochemistry and Molecular Biology Instrumentation, (4) Prototype Construction, (5) Gene and Cell Delivery, and (6) Software Engineering. These components provide instrumentation and skills commonly used by multiple laboratories and are essential to the success of on-going projects as well as to enable new collaborative efforts. They provide tangible support to a diverse array of vision scientists, who are currently supported by 27 active NEI R01 grants, plus additional NEI funding. Purchase of state-of- the-art instruments in the core components has been made possible by the generosity of institutional support, which, in many cases has leveraged extramural support to make a purchase effective. This generosity will continue in the next 5-year period. Support in the form of this Core grant is requested to maintain these instruments through service contracts, and to provide necessary personnel support to assist and train members of core laboratories in the use of the Core facilities.