The Research Ethics Education Program in Jordan

 描述（由申请人提供）：负责任的研究行为（RCR）是发达国家研究培训的基本要求，大多数学术和资助机构要求研究人员在开始研究项目之前获得此类培训约旦是中东和北非（MENA）地区学术上较为成熟的国家之一，人均大学教育和进步的研究议程。它也是制药药物开发的中心，有20多家公司生产仿制药并将其出口到该地区和全球。约旦制药公司在约旦有7个合同研究组织（CRO），进行临床药物试验和相关的人体研究。由于转向西方生活方式和更好地控制传染病，非传染性疾病是约旦的主要死因。约旦是中东和北非地区吸烟率和肥胖率最高的国家之一，这是非传染性疾病的主要风险因素。对研究人员进行负责任地开展研究的培训，对于非传染性疾病预防方面的人口公共卫生研究和与治疗相关的临床试验至关重要。然而，没有适当的道德标准和研究人员培训的研究可能会产生危害而不是好处。约旦在负责任的研究行为和研究道德方面没有可与西方和较发达国家相比的培训。在约旦培训下一代研究科学家将需要在研究伦理培训方面作出持续努力。该提案的目的是：通过建立硕士水平的研究道德来建立个人学习者的能力 该项目的目标是：通过建立一个以公共卫生和临床药物试验为重点的课程体系，提高机构能力，采用循序渐进的教学方法向学习者传授知识;通过将课程和教育材料从英文翻译成阿拉伯文，提高区域能力;建立一个研究伦理案例研究数据库;以及建立一个指导机制，继续吸引毕业生参与。该计划将能够在约旦和该地区开发一个新的研究伦理专业知识骨干。预计至少有120名这样的毕业生将完成该计划，并获得研究伦理学研究生证书。这将涉及约旦的主要合作学术机构-约旦科技大学的能力建设，该大学是约旦和该区域排名最高的研究型大学之一。这将为约旦和该地区的研究人员提供必要的研究伦理范式转变，进一步促进研究生产力，为研究对象提供更好的保护，同时也将RCR的标准提高到国际水平。该计划的总体目标是使参与者能够根据对科学行为和诚信的可接受标准的更多了解做出道德决定。在实现这一目标的同时，该计划将发展机构和区域的教学方法和RCR能力。

 DESCRIPTION (provided by applicant): Responsible conduct of research (RCR) is an essential requirement for research training in developed countries and most academic and funding institutions require researchers to obtain such training before starting a research project Jordan is one of the more academically established countries in the Middle East and North Africa (MENA) region with a high per-capita university education and progressive research agenda. It is also the hub for pharmaceutical drug development with over 20 companies generating generic drugs and exporting it to the region and globally. Jordanian pharmaceutical companies involve 7 Contract Research Organizations (CROs) in Jordan to conduct clinical drug trial and related human research. Non-communicable diseases (NCDs) are the leading cause of death in Jordan because of shifts to a Western lifestyle and better control of communicable diseases. Jordan has one of the highest smoking and obesity rates in the MENA region, which are the leading risk factors for NCDs. The training of researchers in the responsible conduct of research is essential for population public health research in prevention and clinical trials related to treatment of NCDs. However, research without appropriate ethical standards and training of researchers can produce e harm rather than benefit. Jordan does not have training in the area of responsible conduct of research and research ethics that is comparable to Western and more developed countries. Training the next generation of research scientists in Jordan will require sustained effort in research ethics training. The aims of this proposal are: To build capacity of individual learners by creating a master's level research ethics curriculum with a focus on public health and clinical drug trials; To develop institutional capacit by using a step- wise teaching methodology to deliver knowledge to learners; To develop regional capacity by translating curricular and educational material from English to Arabic; Create a database of research ethics case studies; and To establish a mentoring mechanism to continue the engagement of graduates. This program will be able to develop a new cadre of research ethics expertise in Jordan and the region. A minimum of 120 such graduates are expected to finish the program with a graduate-level certificate in research ethics. This will involve capacity building of the main partnering academic institution in Jordan, the Jordan University of Science and Technology which is among the highest ranking research university in Jordan and the region. This will provide the required paradigm shift in research ethics among researchers in Jordan and the region and promote further research productivity and provides better protection of research subjects but also raise the standard of RCR to be at the international level. The overarching goal of the program is to enable participants to make ethical decisions based on increased knowledge of acceptable standards of scientific conduct and integrity. While achieving this goal, the program will develop institutional and regional capacity n teaching methods and RCR.