Buffalo Oral-Research and Specialty Training Program (BORST)

项目摘要/摘要 这是一项新的K12拨款申请，用于支持布法罗口语研究和专业培训 (Borst)计划，这是一项以伦敦大学口腔医学院为基础的综合研究培训计划 布法罗大学(UB)。博斯特的首要目标是促进牙科的发展 专家-科学家学者专注于口腔、牙科和颅面研究。为了实现这一目标，博斯特 提供口腔健康、颅面生物学和 生物工程。博斯特提供了强大的课程和主题研究经验在一个 强调指导、科学进步、学术事业发展、资助人精神、 和生产力。对于这一K12应用程序，我们请求支持牙医从事临床专业工作 牙医科学家在基础、翻译或生物工程科学方面的培训和博士研究培训 对牙齿、口腔或颅面健康很重要。博斯特是牙科医学院不可或缺的一部分， 聘请医学院其他学科和系的教员和实习生/学者，并 伊利诺伊大学生物工程专业。指导和职业发展活动按主题分为5项战略活动 研究重点领域：(一)免疫学和先天防御；(二)口腔病原体与全身的关系 疾病，(三)唾液和唾液腺，(四)口腔生物的微生物致病机制，和(五)骨和 结缔组织/组织工程学。博斯特受益于卓越且久经考验的管理 支助系统和机构承诺，将继续向口语部提供支助 生物学。博斯特计划将在获奖期间支持两名博士后学者，他们将参与 这一结合的职业发展计划。博斯特计划的目标是提供早期职业生涯 为希望从事牙科研究和学术职业的有才华的牙医提供发展 拥有博士学位。将使用一个综合的多年期评价计划来衡量Borst目标的程度 并达到了目标。由此产生的学者将做好充分准备，从事有意义的基础和/或 翻译口腔健康研究。

PROJECT SUMMARY / ABSTRACT This is a new application for a K12 grant that supports the Buffalo Oral-Research and Specialty Training (BORST) Program, an integrated research training program based in the School of Dental Medicine at the University at Buffalo (UB). The overarching objective of BORST is to foster the development of dental specialist-scientist scholars focused on oral, dental and craniofacial research. To accomplish this goal, BORST offers mentored, interdisciplinary research training opportunities in oral health, craniofacial biology and bioengineering. BORST provides a strong curriculum and thematic research experiences in an integrative framework that emphasizes mentoring, scientific advancement, academic career development, grantsmanship, and productivity. For this K12 application, we are requesting support for dentists to engage in clinical specialty training and PhD research training for dentist-scientists in basic, translational or bioengineering sciences important to dental, oral or craniofacial health. BORST is an integral part of the School of Dental Medicine that engages faculty and trainees/scholars in other disciplines and departments in the School of Medicine and Bioengineering at UB. Mentoring and career development activities are thematically grouped into 5 strategic areas of research focus: (i) immunology and innate defenses, (ii) relationship of oral pathogens to systemic disease, (iii) saliva and salivary glands, (iv) microbial pathogenesis of oral organisms, and (v) bone and connective tissues/tissue engineering. BORST benefits from outstanding and time-tested administrative support systems and institutional commitment that will provide continued support to the Department of Oral Biology. The BORST Program will support two postdoctoral scholars over the award period who will engage this combined career development program. The goal for the BORST Program is to provide early career development for talented dentists who wish to pursue research and academic careers as dental specialists with a PhD. An integrated, multi-year evaluation plan will be used to measure the extent to which BORST goals and objectives are met. The resulting scholars will be well prepared to engage in meaningful basic and/or translational oral health research.