Non-invasive intra-cranial pressure measurement

该提案旨在开发一种新的非侵入性测量颅内压的方法，颅内压是许多形式的脑损伤或神经疾病的重要诊断参数。它的工作原理是通过定量视频分析的脉动的主要静脉在眼睛在诱导上升的眼睛压力。我们小组多年的研究已经确定了静脉搏动压力和颅内压之间的关系，并且该信息用于在不需要手术的情况下产生颅内压的精确测量。

This proposal seeks to develop a novel non-invasive method of measuring intra-cranial pressure, an important diagnostic parameter in many form of brain injury or neural disease. It works by quantitative video analysis of the pulsation of the major vein in the eye during induced rises in eye pressure. Many years of study by our group have determined the relationship between vein pulsation pressure and intra-cranial pressure, and this information is used to produce an accurate measurement of intra-cranial pressure without the need for surgery.