Bioinformatics Shared Resource

Harold C.西蒙斯癌症中心 生物信息学共享资源（研究设计和数据分析资源） 项目总结/摘要 癌症中心生物信息学共享资源（CCBSR）设施作为一个尖端的生物信息学 为癌症中心成员提供生物信息学研究设计、数据分析和管理的资源 为西蒙斯癌症中心的基础、转化和临床癌症研究提供支持。该设施有一个 拥有生物信息学、计算机科学、成像分析、统计遗传学和 基因组学、数据库开发和数据管理。CCBSR与其他癌症中心密切合作 共享资源和机构核心设施，为癌症中心提供互补支持 科学计划和疾病导向团队。作为一个新成立的癌症中心共享资源， CCBSR帮助癌症中心实现了其提供高质量生物信息学的使命， 为癌症中心科学计划和疾病导向团队提供分析支持。CCBSR人员 积极参与所有癌症研究项目。自2010年以来，CCBSR已协助超过 90名癌症中心研究人员，参与所有科学项目，提供高质量的生物信息学和分析 支持，这导致了60个同行评审的科学出版物，包括7篇发表在自然， 《科学》、《细胞》和《柳叶刀》。除了他们的个人研究项目，核心成员发挥关键作用， 在7个大型活动的多研究者癌症赠款，包括UT肺孢子。CCBSR开发了 几个临床数据库和基于网络的分析工具，以促进有效的存储，检索， 分析癌症中心研究人员和核心收集的临床和实验室数据，这是必不可少的 转化型癌症研究项目的成功CCBSR还组织每周一次的CCBSR 生物信息学和计算生物学新进展系列研讨会和讲习班，以及 作为CCBSR双周技术讲座系列，重点关注新的生物信息学技术和软件开发。

Harold C. Simmons Cancer Center Bioinformatics Shared Resource (Research Design and Data Analytics Resources) Project Summary/Abstract The Cancer Center Bioinformatics Shared Resource (CCBSR) facility serves as a cutting-edge bioinformatics resource for cancer center members providing bioinformatics research design, data analysis and management support for basic, translational and clinical cancer research in the Simmons Cancer Center. The facility has a team of personnel with expertise in bioinformatics, computer science, imaging analysis, statistical genetics and genomics, database development and data management. The CCBSR works closely with other Cancer Center Shared Resources and institutional core facilities to provide complementary support for the Cancer Center Scientific Programs and Disease-Oriented Teams. As a newly-established Cancer Center Shared Resource, the CCBSR has helped the Cancer Center to achieve its mission in providing high-quality bioinformatics and analysis support for the Cancer Center Scientific Programs and Disease-Oriented Teams. CCBSR personnel have been actively involved in all cancer research programs. Since 2010, the CCBSR has assisted more than 90 Cancer Center Investigators across all scientific programs with high-quality bioinformatics and analysis support, which has led to 60 peer-reviewed scientific publications, including 7 papers published in Nature, Science, Cell and Lancet. In addition to their individual research projects, the core members play critical roles in 7 large active multi-investigator cancer grants, including the UT Lung SPORE. The CCBSR has developed several clinical databases and web-based analysis tools to facilitate the effective storage, retrieval, and analysis of clinical and laboratory data collected by Cancer Center investigators and Cores, which are essential to the success of translational cancer research programs. The CCBSR also organizes a weekly CCBSR research seminar and workshop series on new advances in bioinformatics and computational biology, as well as a CCBSR bi-weekly Tech Talk series focusing on new bioinformatics techniques and software development.