Technologies for Solid-State NMR Data Collection

R&D 2摘要 核磁共振光谱仪的整体性能影响着每一个研究样本和结果。通常是为了 复杂的多维魔角旋转固体核磁共振实验，数十个实验 参数需要仔细调整，并且必须在任何环境条件漂移时重新调整。这里 建议的方法是加快此类实验的设置和配置，以最大限度地利用 可用仪器时间，以及在长时间的信号周期内保持性能 对于仅限量提供的珍贵研究样本可能需要。的方方面面 实验性能也关键依赖于核磁共振探头的设计，包括射频 用于旋转样品、控制温度和均匀输送的电子电路和相关接口 脉冲磁场是现代多维核磁共振实验的一部分。

TR&D 2 SUMMARY The overall performance of the NMR spectrometer impacts every research sample and outcome. Often for complex multidimensional magic-angle spinning solid-state NMR experiments, dozens of experimental parameters require careful adjustment and must be readjusted anytime the environmental conditions drift. Here proposed are approaches to accelerate the setup and configuration of such experiments to maximally leverage the available instrument time, as well as to maintain performance over long periods of signal averaging that can be required for precious research samples that are available only in limited quantity. All aspects of the experimental performance also rely critically on the NMR probe designs, including the radiofrequency electronic circuits and related interfaces to spin the sample, control the temperature and deliver homogeneous pulsed magnetic fields as part of modern multidimensional NMR experiments.