Core A: Administrative Core

摘要/摘要-管理核心 行政核心将负责密歇根州的全面领导和科学监督 肥胖和糖尿病活体模型的代谢表型(Mi-MPMOD)中心。核心将提供 对动物护理和无菌核心以及新陈代谢、生理和健康的行政援助 行为(MPB)表型核心，并确保他们的服务得到高效和最高的交付 可能的标准。领导团队拥有丰富的管理经验，并位于 伊丽莎白·W·卡斯韦尔糖尿病研究所(CDI)的北校园研究综合体，毗邻 密歇根州糖尿病研究中心(MDRC)、密歇根州营养和肥胖中心的行政核心 研究中心(MNORC)和CDI。相关管理核心的这种集群有助于高效地 使用空间和设备，并利用所有中心管理员的集体经验，确保 在它们之间转让最佳做法。行政核心将：a)协调动物的接收和 分配适当的表型鉴定服务；b)监测研究进展，直至完成数据 分析并向提出请求的调查员(S)提交最终报告；c)确保安全处理和 签署所有必要的使用条件声明、合同、服务费和数据记录以及 向MPMOD联合会和协调股数据库提交后续数据；d)管理 预算和工作流程记录，监督成本回收、方案收入和服务费调整； E)根据核心服务活动和科学需求重新编制中心资金预算；f)促进提供 为当地调查人员、区域合作伙伴和全国性研究机构提供的MPMOD资源，包括 学术和营利性生物技术和制药公司；g)制定沟通战略，以 具体针对代表性不足的绩效指标和小型实验室或机构，这些机构没有收到显著 通过广告、研讨会和与学术部门的直接联系为联邦研究提供资金； H)促进为中心的MPB开发新的研究技术和培训资源 表型鉴定核心；和i)定期与咨询委员会举行会议，监督筹备和 向NIDDK提交年度进度报告。行政核心将与各中心密切合作 财团和国家CU积极参与征集和审查申请 MPMOD财团的资金计划。它还将与财团和CU协同工作，以尽量减少 服务重叠，并建立、标准化、记录和分发表型鉴定协议和质量 全国范围内实验室的控制程序。

Abstract/Summary – Administrative Core The Administrative Core will be responsible for the overall leadership and scientific oversight of the Michigan Metabolic Phenotyping of live Models of Obesity and Diabetes (Mi-MPMOD) Center. The Core will provide administrative assistance to the Animal Care and Germ-Free Core and the Metabolic, Physiological and Behavioral (MPB) Phenotyping Core and ensure that their services are delivered efficiently and to the highest possible standards. The leadership team has extensive administrative experience and is centrally located in the North Campus Research Complex at the Elizabeth W. Caswell Diabetes Institute (CDI), adjacent to administrative cores of the Michigan Diabetes Research Center (MDRC), the Michigan Nutrition and Obesity Research Center (MNORC) and the CDI. This clustering of related Administrative Cores facilitates an efficient use of space and equipment and leverages the collective experience of all centers’ administrators assuring the transfer of best practices among them. The administrative core will: a) Coordinate the receipt of animals and assignments for the appropriate phenotyping services; b) monitor studies progress until completion of data analysis and submission of final reports to the requesting investigator(s); c) ensure secure processing and signing of all necessary conditions of use statements, contracts, service fees, and data records as well as the subsequent data submission to the MPMOD Consortium and Coordinating Unit (CU) database; d) manage budgetary and workflow records, oversee cost recovery, program income and adjustment of service charges; e) re-budget Center funds based on the cores service activity and scientific needs; f) promote the availability of MPMOD resources to local investigators, regional partners, and nationwide research institutions, including academic and for-profit biotechnology and pharma companies; g) develop communication strategies to specifically target underrepresented PIs and small laboratories or institutions that have not received significant federal research funding through advertisement, seminars, and direct contact with the academic departments; h) facilitate the development of new research technology and training resources for the Center’s MPB Phenotyping Core; and i) meet regularly with the Advisory committees and oversee the preparation and submission of annual progress report to NIDDK. The Administrative Core will work closely with the Centers’ Consortium and the national CU by actively participating in the solicitation and review of applications for the MPMOD Consortium’s funding programs. It will also work in synergy with the Consortium and CU to minimize overlap of services and establish, standardize, document, and distribute phenotyping protocols and quality control procedures to laboratories nationwide.