2020-2022 Biomedical Engineering Society (BMES) Cellular and Molecular (CMBE) Conference

摘要 此应用程序的目标是支持学生、研究员和早期调查人员的旅行奖励 (ESI)出席细胞和分子生物工程(CMBE)会议。会议的具体主题是 2020年会议的主题是“2020愿景：阐明生命法则的新兴技术”。选择 主题旨在解决新的新兴技术如何帮助我们 设计更好的生物系统来改变我们对生命规则的理解，以及翻译 最终造福人类健康的新发现。最近，许多新技术已经 已经开发了基因组/表观遗传学编辑、单细胞到组织水平的细胞图谱、操纵工具 细胞外环境以及在3D中制造细胞/组织结构的方法。在这个中心主题中，一个 广泛的孤立群体出现在不同的学科中，但尚未完全参与 CMBE社区。这次会议的需要在于将这些调查人员带来的独特机会 首次齐聚一室，交流思想，集思广益，推动新的联合战略 分子和细胞工程领域正迈向一个新的整合水平。选举的结果是 会议将增加研究人员之间的技术分享，以及新的愿景和战略 为基础科学和临床翻译设计生物系统的计划。 这个R13应用程序的具体目标有两个。第一是为八个ESI提供支持 初级调查人员和12名博士后研究员或研究生，他们提交的论文将 根据科学功绩被选为领奖人，重点是促进妇女和 代表不足的少数族裔。会议将为这些调查人员提供必要的接触和 指导他们开始或扩大他们的学术研究事业。第二个目标是促进采用 向CMBE研究界提供新技术，促进跨学科合作。 会议将提供一个平台，让工程、化学、生物和数据科学的研究人员了解情况 以最新的技术和开发一种途径来增加CMBE在人类疾病研究中的影响。 目标1：向不同的工程和生物学展示变革性的CMBE发现和技术 观众。受邀的演讲者将在演讲期间讨论他们的最新研究，并特别强调 关于工程生物系统的新原则或新规则。 目标2：概述将基础CMBE研究转化为诊断和治疗的潜在途径 人类疾病。这将为如何联系研究人员提供指导，实际上是整个CMBE领域， 配合临床医生和产业界加大翻译这一研究领域的力度。 研究结果将发表在《BMES细胞和分子生物工程杂志》的特刊上。

Abstract The goal of this application is to support travel awards for students, fellows, and early stage investigators (ESI) to attend the Cellular and Molecular Bioengineering (CMBE) Conference. The specific theme of the 2020 conference will be ‘Vision 2020: Emerging Technologies to Elucidate the Rules of Life. The choice of theme is intended to address the key problem of how the new emerging technologies can help us to engineer better biological systems to transform our understanding of rule of life, as well as translate new discoveries in ways that ultimately benefit human health. Recently, many new technologies have been developed such as genomic/epigenetic editing, single cell to tissue-level cell atlas, tools to manipulate extracellular environment, and methods to fabricate cell/tissue structure in 3D. Within this central theme, a broad spectrum of isolated groups has emerged from disparate disciplines but has not been fully engaged in the CMBE community. The need for this conference lies in the unique opportunity to bring these investigators together in one room for the first time to exchange ideas and brainstorm new combined strategies for pushing the field of molecular and cellular engineering forward to a new level of integration. The outcome of the conference will be increased technology sharing amongst researchers, as well as a new vision and strategic plan for engineering biological systems for basic science and clinical translation. The specific objectives of this R13 application are two-fold. The first is to provide support to eight ESI junior investigators and twelve postdoctoral fellows or graduate students, whose submitted papers will be selected for podium presentation on the basis of scientific merit, with a focus on promoting women and underrepresented minorities. The meeting will provide these investigators with essential exposure and mentoring to launch or expand their academic research careers. The second objective is to foster adoption of new technologies to the CMBE research community and promote the interdisciplinary collaboration. The meeting will provide a platform to expose researchers in engineering, chemistry, biology, and data science to the latest techniques and develop a pathway to increase the impact of CMBE research in human disease. Aim #1: Present transformative CMBE discoveries and techniques to a diverse engineering and biology audience. Invited speakers will discuss their latest research during their presentations, with a special emphasis on new principles or rules in engineering biological systems. Aim #2: Outline potential pathways to translate fundamental CMBE research into diagnostics and therapies in human disease. This will provide guidelines in how to connect researchers, and in fact the entire CMBE field, with clinicians and industry to increase translation of this research area. Outcomes will be published in a special issue of the BMES Cellular and Molecular Bioengineering Journal.