Core A: Administrative Core

摘要：行政核心 行政核心负责监督堪萨斯大学的运营和战略规划 阿尔茨海默病研究中心(KU ADRC)。在十多年的P30支持下，Core实现了增长 这让我们成为AD线粒体/新陈代谢、生活方式干预和预防研究的领先者。 支持这些计划需要我们开发和实施独特的基础设施，以促进 专门的分子、临床试验、招募、教育和病人护理计划。 除了定义中心战略外，核心还管理支持我们的 调查人员。这包括生物检疫采购计划；同意和合规要求；确保 生物检疫存储；以及促进对生物检疫、数据、咨询和其他中心服务的访问。 我们为我们的其他核心提供建议，监控他们的生产率，并促进他们的无缝和协同合作。 我们验证NIA的计划义务得到有效履行，并维护内部和外部咨询 委员会。到目前为止，我们运行了一个非常成功的试点项目计划；从2011年到2019年 我们看到40名试点受助人中有27人(68%)获得了外部赠款支持。核心确保所有KU ADRC 各组成部分获得充足的财政资源。除了管理我们的P30预算外，我们还通过 确定并从机构ADRC利益攸关方获得美元，发展慈善事业，并提交 P30补充剂。 无论是设计战略、追踪资金、确定空间、建设资源、开发 调查人员，或发展中心并推进其议程，行政核心在以下方面发挥不可或缺的作用 KU ADRC在短期和长期都取得了成功。在过去的10年里，我们清楚地将AD、AD相关、 和堪萨斯大学的大脑老化研究。在我们的下一个周期中，我们将继续我们的轨迹 引导的战略性增长，推动AD研究领域的发展，使我们更接近有效的治疗和 预防策略。我们将通过专注于一套明确的具体目标来实现这些目标 包括：(1)管理基础设施和日常运营；(2)开发和增强知识产权 资产；以及(3)确定目标和扩大影响。

ABSTRACT: ADMINISTRATIVE CORE The Administrative Core oversees operational and strategic planning for the University of Kansas Alzheimer's Disease Research Center (KU ADRC). Over a decade of P30 support, the Core managed growth that saw us become a leader in AD mitochondria/metabolism, lifestyle intervention, and prevention research. Supporting these programs required us to develop and implement unique infrastructure that promotes specialized molecular, clinical trial, recruitment, education, and patient care initiatives. In addition to defining Center strategy, the Core manages the resources needed to support our investigators. This includes biospecimen procurement plans; consent and compliance requirements; ensuring biospecimen storage; and facilitating access to biospecimens, data, consultation, and other Center services. We advise our other cores, monitor their productivity, and promote their seamless and synergistic cooperation. We verify NIA programmatic obligations are efficiently met and maintain Internal and External Advisory Committees. Up to this point we ran an immensely successful pilot project program; from 2011 through 2019 we saw 27 of 40 (68%) of our pilot recipients receive external grant support. The Core ensures all KU ADRC components receive adequate financial resources. Beyond managing our P30 budget, we accomplish this by identifying and procuring dollars from institutional ADRC stakeholders, developing philanthropy, and submitting P30 supplements. Whether designing strategy, tracking down dollars, identifying space, building resources, developing investigators, or growing the Center and advancing its agenda, the Administrative Core plays an integral role in both short-and-long term KU ADRC successes. Over the past 10 years we clearly transformed AD, AD-related, and brain aging research at the University of Kansas. During our next cycle we will continue our trajectory of guided, strategic growth that advances the AD research field and moves us closer to effective treatments and prevention strategies. We will accomplish these goals by focusing on a defined set of specific aims that include: (1) Managing infrastructure and routine operations; (2) Developing and empowering intellectual assets; and (3) Defining goals and amplifying impact.