Novel function of heat shock protein 2A in the regulation of human sperm-egg interactions

男性不育是一种极其常见的疾病，大约每20名澳大利亚男性中就有1人患有这种疾病。这种病理的一个主要原因是精子已经失去了识别卵子的能力。在这个项目中，我们将研究这种缺陷是否由于缺乏一种特定的蛋白质（HSPA2）。该项目将为男性不育的原因提供新的有力的见解，对这种疾病的预防、诊断和治疗具有实际意义。

Male infertility is an extremely common condition affecting around 1 in 20 Australian men. One of the major reasons for this pathology is that the spermatozoa have lost their ability to recognize the egg. In this project we shall investigate whether this defect is due to a deficiency in a specific protein (HSPA2). This project will provide new and powerful insights into the causes of male infertility, with practical implications for prevention, diagnosis and treatment of this condition.