Chemistry and Biology Interface (CBI) NIH T32 Training Grant

CBI T32摘要：化学-生物学接口(CBI)博士前项目的目标 是为具有不同兴趣的有才华的学生提供跨学科培训，这将使 他们将化学的机械论和原子论观点应用于重要的生物学 有问题。该项目汇集了来自大学八个学术单位的42名教员培训人员。 代表有机化学、分析化学、生物化学、 化学生物学、结构生物学、分子生物学、细胞生物学、系统生物学、 生物信息学、分子生物学、细胞生物学、微生物学、病毒学和发育生物学。 教员培训人员既包括新老的研究人员，也包括有活力的研究项目的研究人员。 生物分子科学和研究生培养经验。多元化的实习生群体 (重点是招聘和留住URM)具有不同教育背景的 他们渴望探索化学和化学之间的多学科问题的基础 生物学，他们的GRE成绩，本科GPA，推荐信和研究 背景资料。每年有八名学员通过现有的研究生课程录取 化学与生物化学、化学与生物分子工程、生物科学或其他 CBI培训师部门和大学为他们的第一年提供了支持。第二个由资金资助的轨道 CBI项目的录取情况；对研究有强烈兴趣的学生在 化学和生物接口将被邀请申请在他们的一年级或二年级结束 他们的研究生课程。所有受训人员将满足其特定专业的学位要求 除了对CBI计划的要求外，还包括部门计划。三个一学期 课程将从六个部门提供的不同课程列表中挑选出来。一项关键功能 CBI计划的核心是每个学员进行的实验室轮换，以提供他们的双手- 关于不同学科的经验。在课程和实验室轮换之间，学生们 期望能够接触到从原子论到细胞学的概念和方法。学生 被这种背景赋予了创造性地思考生物和化学问题的能力 与人类健康相关的物质。这项建议旨在为学生提供大学菜单 资助实习(当地制药/生物技术公司、国家实验室和新的合作伙伴，以 加强他们的职业发展。所有受训人员都被要求参加一系列的季度 负责任的研究行为(RCR)研讨会，为期2天的大学赞助的RCR和 1月举办的数据可重复性和严谨性研讨会。每周一次的研讨会系列为CBI带来了 社区在一起，并为学员提供大量机会介绍他们自己的工作，如 我们还可以从教员培训师和外部演讲者那里学习。每个实习生都要承担一项 密集的独立研究经验，最终形成一篇代表原创的论文 对化学-生物交界处的一个领域的贡献。该计划遵循并建立在 成功的25年模式，培养既有广泛科学知识又有 在选定的核心学科方面有扎实的基础。通过这份指导补充材料，我们的目标是扩大 我们在导师培训方面的努力，注重文化意识的辅导，并创造一个环境 在那里，支持性的指导是被拥护的。

CBI T32 Abstract: The objective of this Chemistry-Biology Interface (CBI) Predoctoral Program is to provide cross-disciplinary training to talented students with diverse interests that will enable them to apply the mechanistic and atomistic perspective of chemistry to important biological problems. The program brings together 42 faculty trainers from eight academic units at the Univ. of Delaware representing disciplines of organic chemistry, analytical chemistry, biochemistry, chemical biology, structural biology, molecular biology, cell biology, systems biology, bioinformatics, molecular biology, cell biology, microbiology, virology, and developmental biology. The faculty trainers include both new and established researchers with vibrant research programs in biomolecular science and experience in training graduate students. A diverse trainee group (with a focus to recruit and retain URMs) with varied educational backgrounds are selected on the basis of their desire to explore multidisciplinary problems at the interface of chemistry and biology, their GRE scores, undergraduate GPA, letters of recommendation and research background. Eight trainees are admitted each year through existing graduate programs of Chemistry & Biochemistry, Chemical & Biomolecular Engineering, Biological Sciences or other CBI trainer departments and university supported for their first year. A second, funded track of admission to the CBI program is outlined; students with a strong interest in research at the interface of chemistry and biology will be invited to apply at the end of their first or second year of their graduate studies. All trainees will satisfy the degree requirements for their specific departmental program in addition to the requirements for the CBI program. Three one semester courses will be selected from a diverse list of course offerings from six departments. A key feature of the CBI program is the laboratory rotations each trainee undertakes to provide them with hands- on experience in the different disciplines. Between courses and laboratory rotations students are expected to have exposure to concepts and methods from the atomistic to the cellular. Students are empowered by this background to think creatively about biological and chemical problems that are relevant to human health. This proposal aims to provide students with a menu of university funded internships (local pharmaceutical/biotech firms, National Labs and new collaborations to enhance their career development. All trainees are required to participate in a series of quarterly responsible conduct of research (RCR) workshops, a 2-day University sponsored RCR and a January workshop of data reproducibility and rigor. A weekly seminar series brings the CBI community together and provides trainees numerous opportunities to present their own work, as well as learn from both faculty trainers and outside speakers. Each trainee undertakes an intensive independent research experience culminating in a dissertation representing an original contribution to a field at the chemistry-biology interface. This program follows and builds on a successful 25-year model for training scientists with both broad scientific knowledge as well as solid foundations in a chosen core discipline. With this Mentoring Supplement, we aim to broaden our efforts in mentor training with a focus on culturally aware mentoring and create an environment where supportive mentoring is championed.