TREAT (Time Restricted EATing) to improve cardiometabolic health

摘要 促进健康相关研究多样化的研究副刊对父母的资助 1R01AG065569-02A1将为Santos-Báez博士的培训提供支持。两年制 《促进多样性研究补编》的持续时间受若干因素驱动 包括必要数量的必要培训：1)临床研究的基础知识(伦理学， IRB应用，负责任的研究，严格的数据收集和数据记录， 制定程序手册)；2)能量平衡和葡萄糖的评估方法 父母拨款中使用的新陈代谢；3)与项目相关的文献的批判性审查；4) 统计分析原理；5)摘要、海报、稿件的科学写作。这个 本补充资料的时间将与5年父母R01的第3年和第4年(结束日期)重合 2025年6月30日)。拟议的多样性补编将提供必要的设计和培训 对患有肥胖症和糖尿病前期的老年人进行了一项限时进食的临床试验。 桑托斯-贝兹博士的职业目标是成为一名独立的调查员 跨学科研究，特别关注成为新陈代谢预防领域的领导者 脆弱人群中的疾病。最终，完成这项建议将为您的职业生涯奠定基础 肥胖和代谢障碍的发展轨迹。在完成为期两年的培训后， 应聘者应能够提出新的假设，提出适当的研究设计，并 方法检验这些假设，并编写一个K奖应用程序。

Summary The Research Supplement to Promote Diversity in Health-Related Research to the parent grant 1R01AG065569-02A1 will provide support for the training of Dr Santos-Báez. The 2-year duration of the Research Supplement to Promote Diversity is driven by a number of factors including the necessary amount of required training in: 1) The ABC of clinical research (ethics, IRB applications, responsible conduct of research, rigor of data collection and data recording, establishing a manual of procedure); 2) Methods for assessment of energy balance and glucose metabolism used in the parent grant; 3) Critical review of literature pertinent to the project; 4) Principle of statistical analyses; 5) Scientific writing of abstracts, poster and manuscripts. The timing of this Supplement will coincide with year 3 and 4 of a 5-year parent R01 (end date 6/30/2025). The proposed Diversity Supplement will provide needed training in the design and execution of a clinical trial of time restricted eating in older adults with obesity and prediabetes. The career goal of Dr. Santos-Báez is to become an independent investigator conducting interdisciplinary research with a specific focus on becoming a leader in prevention of metabolic diseases in vulnerable populations. Ultimately, completion of this proposal will establish career launching trajectory in obesity and dysmetabolism. At the completion of the 2-year training, the candidate should be able to develop novel hypotheses, propose appropriate study design and methods to test these hypotheses, and write a K award application.