CENTER FOR PERCEPTION AND COMMUNICATION IN CHILDREN

项目总结/摘要 总体：儿童感知和交流中心 儿童感知与沟通中心（CPCC）第二阶段的目标是，我们的中心 奥马哈博伊斯镇国家研究医院（BTNRH）的卓越生物医学研究（COBRE）， 内布拉斯加州，是扩大目前的研究计划的范围，提供一个独特的环境， 发展初级教师谁有兴趣确定机制和因素，影响 儿童的听觉和视觉感知以及交际发展。这一重点反映了一种迫切需要， 用于翻译，多学科研究，调查沟通障碍儿童的结果。 我们的目标是继续扩大我们的研究计划范围，最终成为全国领先者 研究言语，语言，听力和认知发展的儿童与沟通 紊乱我们实现这一目标的方法是建立和支持独立但互补的， 研究计划，解决（1）影响言语，语言，听力和认知的因素 （2）儿童听力损失和发育性语言障碍对言语的影响， 语言，听力和认知功能在现实世界中的环境，和（3）策略，以提高儿童的 言语、语言、听力和认知结果。我们将通过开发和支持一个关键的 美国国立卫生研究院资助的大量研究项目集中在与儿童感知和沟通有关的问题上。 我们还将在第二阶段加强核心领导人可用的研究基础设施，并扩大用户 这些资源的基础，包括建立CPCC调查员。 第二阶段的四个初始项目将调查与以下方面有关的问题：（1）促进 人工耳蜗植入者的言语理解，（2）儿童的鉴别诊断和结果 中耳炎，（3）年龄的影响，在知觉和语言机制的基础上，视觉 语音增强，以及（4）儿童用于克服复述策略的个体差异 工作记忆的局限性关于这些专题的研究将由三个核心提供便利。核心A， 行政核心，将协调与外部咨询委员会、行政核心 咨询委员会、内部执行委员会和研究导师。核心B，即技术核心， 将为硬件和软件开发、数据分析和室内声学问题提供支持。核心C， 人类受试者核心，将收集临床数据，实施质量保证程序，并协助 临床测量的选择和解释以及研究参与者的招募。的 CPCC将继续受益于高级教师的综合研究经验，他们将担任 核心领导和导师，并从独特的患者资源和转化研究环境， BTNRH。

PROJECT SUMMARY/ABSTRACT OVERALL: CENTER FOR PERCEPTION AND COMMUNICATION IN CHILDREN The goal of Phase II of the Center for Perception and Communication in Children (CPCC), our Center of Biomedical Research Excellence (COBRE) at the Boys Town National Research Hospital (BTNRH) in Omaha, Nebraska, is to expand the range of the current research program by providing a unique environment for the development of junior faculty who have an interest in identifying mechanisms and factors that influence children’s auditory and visual perception and communicative development. This focus reflects a critical need for translational, multi-disciplinary research investigating outcomes for children with communication disorders. Our goal is to continue to expand the scope of our research programs, ultimately becoming the national leader for research on speech, language, hearing, and cognitive development in children with communication disorders. Our approach for achieving this goal is to build and support independent, yet complementary, research programs that address (1) factors that influence speech, language, hearing, and cognitive development, (2) the impact of childhood hearing loss and developmental language disorders on speech, language, hearing, and cognitive functions in real-world environments, and (3) strategies to improve children’s speech, language, hearing, and cognitive outcomes. We will do this by developing and supporting a critical mass of NIH-funded research programs focused on issues related to perception and communication in children. We will also strengthen the research infrastructure available to Core Leads in Phase II, and extend the user base of these resources to include established CPCC investigators. The four initial projects in Phase II will investigate issues related to (1) cognitive mechanisms that facilitate speech understanding for listeners with cochlear implants, (2) differential diagnosis and outcomes for children with otitis media, (3) age effects in the perceptual and linguistic mechanisms that underlie auditory-visual speech enhancement, and (4) individual differences in the rehearsal strategies used by children to overcome working memory limitations. Research on these topics will be facilitated by three cores. Core A, the an Administrative Core, will coordinate interaction with an External Advisory Committee, an Administrative Advisory Committee, an internal Executive Committee, and research mentors. Core B, the Technology Core, will provide support for hardware and software development, data analysis, and room-acoustics issues. Core C, the Human Subjects Core, will collect clinical data, implement quality assurance procedures, and assist with selection and interpretation of clinical measures and recruitment of participants for research studies. The CPCC will continue to benefit from the combined research experience of the senior faculty who will serve as Core Leads and mentors, and from the unique patient resources and translational research environment at BTNRH.