Pilot and Feasibility Program

摘要 拟议的试点和可行性(P/F)计划是NIDDK支持的类似努力的延伸- 加州大学圣地亚哥分校(UCSD)资助的迷你中心为期四年及以后 利用机构资源延长该方案。鉴于过去和现在方案的成功， 我们已收到机构承诺，将西尔维奥·O·孔特中心提供的资金增加一倍 在消化系统疾病研究方面，支持年轻科学家开始他们的职业生涯的创新的新奖项。 P/F方案还将用于吸引具有杰出专业知识的调查人员进入消化领域。 关注胃肠道和肝脏炎症这一中心主题的疾病研究。这个 P/F计划的目标是使大量有才华的研究人员和 圣地亚哥消化疾病研究中心内有前途的受训人员并促进过渡 从试点项目到由外部来源资助的研究补助金。为了实现这一目标，我们将使用P/F 科学审查委员会由中心外经验丰富的教师担任主席。这个组织的成员 委员会将来自内部咨询委员会，除其他外代表所有专题领域和机构 加州大学圣迭戈分校。公告将在每个学校的教职员工截止日期之前提前广泛广播 中心机构。所有申请都将由该领域的专家进行审查，每个申请将包括一份 从中心外进行审查。P/F科学审查委员会主席将列出分数和 召开会议讨论排名和预算。将向执行人员推荐一项薪酬计划 并与外部咨询委员会进行了讨论，并将宣布奖项。获奖后， P/F计划主任将跟踪没有资金的申请者，讨论未来的改进 考虑因素。此外，P/F计划主任和一名或多名核心主任和联席主任 将每年与每位获奖者举行两次会议，审查进展情况，鼓励他们获得专业知识，并 在核心内部提供服务，并注意它们在申请外部资金方面取得的进展。因此，P/F 该计划将通过提供资金支持新的项目和职业生涯，使中心的研究人员大大受益 有关消化道和肝脏的研究进展。

Summary The proposed Pilot and Feasibility (P/F) Program is an extension of the similar effort supported by the NIDDK- funded Mini-Center held at the University of California San Diego (UCSD) for four years and subsequent extension of the Program with institutional resources. In view of the success of the past and current Program, we have received outstanding institutional commitment to double the funds provided by a Silvio O. Conte Center in Digestive Disease Research to support innovative new awards for young scientists beginning their careers. The P/F program will also be used to attract investigators with outstanding expertise into the area of digestive diseases research that is focused on the central theme of inflammation in the gastrointestinal tract and liver. The objective of the P/F Program is to make research funds available to a broad swath of talented investigators and promising trainees within the San Diego Digestive Diseases Research Center and to facilitate the transition from pilot projects to research grants funded by extramural sources. To achieve this objective, we will use a P/F Scientific Review Committee chaired by an experienced faculty from outside of the Center. The members of this committee will be from the Internal Advisory Board and represent all thematic areas and institutions in addition to UCSD. Announcements will be widely broadcast well in advance before deadlines to the faculty in each of the Center institutions. All applications will be reviewed by experts in the field and each application will include a review from outside the Center. The Chair of the P/F Scientific Review Committee will tabulate scores and convene a meeting to discuss rankings and budgets. A pay plan will be recommended to the Executive Committee and discussed with the External Advisory Committee, and awards will be announced. Post-award, the Director of the P/F Program will follow up with unfunded applicants to discuss improvements for future considerations. In addition, the P/F Program Director and one or several of the Core Directors and Co-Directors will meet twice a year with each awardee to review progress, encourage them to access the expertise and services within the Cores and note their progress towards an application for extramural funding. Thus, the P/F Program will greatly benefit the investigators in the Center by providing funds to support new projects and career development in research related to the digestive tract and liver.