A lifecourse approach to women's mental health: from fertility to perimenopause

项目摘要/摘要 不孕不育及其治疗通常是长期的，可能会对心理构成挑战。因此，许多人 女性报告说，她们在尝试时感到痛苦、失控、社会孤立和耻辱感 没能成功怀孕。然而，人们对生育力受损对长寿的影响知之甚少。 长期心理健康结果。有限的纵向数据表明生育力受损与 焦虑和抑郁症状在怀孕、产后和中年的轨迹。另外， 诸如虐待、缺乏社会支持、经济困难和种族主义经历等困难是众所周知的。 与抑郁和焦虑症状密切相关，然而这些因素如何与 女性一生中生育能力受损的经历尚不清楚。 这份多样性副刊将为候选人佩雷斯·卡波托斯托博士提供额外的经验， 专业知识、技能和数据有助于实现她成为该领域独立护士科学家的目标 生育能力受损的症状。Pérez Capotosto博士将利用她的背景和经验来检查效果 生育力受损对长期心理健康结果的影响。具体地说，她将调查 有生育力减退史妇女与无生育史妇女的抑郁和焦虑情绪比较 生育力受损的风险，以及抑郁和/或焦虑与整个生育力受损妇女的相关性 生命的长短。在这样做的过程中，她将检查早期生活困难的影响，例如虐待史、缺乏 社会支持、经济困难和种族主义经历与抑郁和焦虑的关系 在生育能力受损的女性中。这项提案的数据已在Viva项目队列中收集 通过“女性心脏代谢和骨骼健康的生命周期方法：从生育到围绝经期” (5R01HD096032-03)，家长资助。作为家长赠款的私人情报员，艾米丽·奥肯博士和豪尔赫·查瓦罗博士 将指导佩雷斯·卡波托斯托博士。候选人还将接受安·沃尔伯特·伯吉斯博士的指导 波士顿学院W.F.康奈尔护理学院精神病学心理健康护理学教授。使用 她将通过拟议的多样性补充方案获得的培训、技能和经验，佩雷斯博士 Capotosto打算从临床学术职位转向研究学术职位。

Project Summary/Abstract Infertility and its treatments are often long-lasting and can be psychologically challenging. Consequently, many women report feelings of distress, loss of control, social isolation, and a sense of stigma as they try unsuccessfully to achieve pregnancy. However, little is known about the effects of impaired fertility on long- term mental health outcomes. Limited longitudinal data exist on the associations of impaired fertility with trajectories of anxiety and depressive symptoms across pregnancy, postpartum, and mid-life. Additionally, hardships such as abuse, lack of social support, financial hardship, and the experiences of racism are known to be strongly associated with symptoms of depression and anxiety, yet how these factors interact with the experience of impaired fertility in women across their life course is not known. This Diversity Supplement will provide the candidate, Dr. Pérez Capotosto, with the additional experience, expertise, skills, and data necessary to facilitate her goal to become an independent nurse scientist in the field of impaired fertility. Dr. Pérez Capotosto will draw upon her background and experience to examine the effects of impaired fertility on long-term mental health outcomes. Specifically, she will investigate the associations of depression and anxiety among women with a history of impaired fertility compared to women without a history of impaired fertility, and the relevance of depression and/or anxiety in women with impaired fertility throughout the lifespan. In doing so, she will examine the effects of early life hardship, such as the history of abuse, lack of social support, financial hardship, and experiences of racism, on the associations of depression and anxiety among women with impaired fertility. Data for this proposal have been collected in the Project Viva cohort through, “A lifecourse approach to women's cardiometabolic and bone health: from fertility to perimenopause” (5R01HD096032-03), the parent grant. As the PIs of the parent grant, Dr. Emily Oken and Dr. Jorge Chavarro will mentor Dr. Pérez Capotosto. The candidate will also receive mentorship from Dr. Ann Wolbert Burgess, a Professor of Psychiatric Mental Health Nursing in the W.F. Connell School of Nursing at Boston College. With the training, skills, and experience she will receive through the proposed diversity supplement, Dr. Pérez Capotosto intends to move from a clinical academic position to a research academic position.