Nurses Health Study 3: A multiple exposure environmental epidemiology cohort of young adults
护士健康研究 3:年轻人多次暴露环境流行病学队列
基本信息
- 批准号:10440077
- 负责人:
- 金额:$ 5.9万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2021
- 资助国家:美国
- 起止时间:2021-09-10 至 2022-06-30
- 项目状态:已结题
- 来源:
- 关键词:2019-nCoVAddressAdministrative SupplementAdolescenceAreaBig Data MethodsBiologicalBloodCOVID-19 testingCanadaCharacteristicsChronic DiseaseCollectionDataData CollectionDietEnrollmentEnvironmentEnvironmental EpidemiologyEnvironmental ExposureEnvironmental Risk FactorEnvironmental and Occupational ExposureFecesFemaleIndividualInfectionInfrastructureInfrastructure ActivitiesInvestigationKnowledgeLife Cycle StagesMeasurementMenopauseModernizationMonoclonal Antibody R24Nurses&apos Health StudyOnline SystemsParentsParticipantPhysical activityPregnancyPregnancy HistoriesProspective cohort studyPsychosocial FactorResearchResearch PersonnelResourcesRisk FactorsRoleSARS-CoV-2 antibodySamplingSpecimenSymptomsTechnologyTechnology AssessmentTimeUncertaintyUnited StatesUrineVial devicecohortcost effectivedisorder riskexperiencegeographic riskinnovationmobile computingnoveloperationparent projectprospectiveresidencesample collectionyoung adult
项目摘要
PROJECT SUMMARY OF PARENT PROJECT (R24ES028521)
This is an R24 application to support the infrastructure of our environmental epidemiology cohort,
Nurses’ Health Study 3 (NHS3), an open, prospective, web-based cohort (www.nhs3.org).
Participants are residence of the United States and Canada born after 1965. Most of the female
participants (89%) have enrolled before menopause and 41% of female participants and 62% ofmale
participants have no prior pregnancy history. In this innovative web-based study, we have been
collecting detailed information on personal characteristics and potential disease risk factors every 6
months, including diet, physical activity, psychosocial factors, and a wide variety of occupational
and environmental exposures. Data collection has focused on current exposures, as well as those
experienced during adolescence, prior to first pregnancy, and during pregnancy.Discoveries made in
NHS3 will build on the knowledge and experience gained from earlier cohorts on the impacts of
the environment on chronic disease risk but takes advantage of modern technology to collect novel
prospective data during important windows of exposure across the life course. The NHS3
investigators have substantial experience in environmental epidemiology,exposure assessment, and
Big Data analytics, as well as in managing and maintaining large prospective cohort studies. This
cohort provides a unique opportunity to address key outstanding questions in environmental
epidemiology, by collecting highly detailed information on multiple environmental exposures at
key points in the life course.
The R24 supports infrastructure activities in the expanded NHS3 cohort thatmaximize the existing
resources and broaden the current scope of research, to allow the investigation of multiple
environmental exposures. We will focus our efforts in three main areas: 1) the expansion of study
operations and maximization of existing resources, 2) the collection of environmental exposure
samples, and 3) expansion of web-based mobile technologies and assessment of spatial uncertainty
and measurement error. We have partnered with U01HL145386 to collect biologic samples (blood,
urine, stool) concurrently with the environment exposure samples. This administrative supplement will
allow us to prepare cost-effective lab-ready vials of both biologic and environmental specimens at the
time of collection.
母项目项目总结(r24es028521)
项目成果
期刊论文数量(6)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Occupational exposure to high-level disinfectants and risk of miscarriage among nurses.
- DOI:10.1136/oemed-2020-107297
- 发表时间:2021-10
- 期刊:
- 影响因子:4.9
- 作者:Ding M;Lawson C;Johnson C;Rich-Edwards J;Gaskins AJ;Boiano J;Henn S;Rocheleau C;Chavarro JE
- 通讯作者:Chavarro JE
Occupational use of high-level disinfectants and asthma incidence in early- to mid-career female nurses: a prospective cohort study.
- DOI:10.1136/oemed-2020-106793
- 发表时间:2021-04
- 期刊:
- 影响因子:4.9
- 作者:Dumas O;Gaskins AJ;Boggs KM;Henn SA;Le Moual N;Varraso R;Chavarro JE;Camargo CA Jr
- 通讯作者:Camargo CA Jr
Demographic and behavioural correlates of energy drink consumption.
- DOI:10.1017/s1368980022001902
- 发表时间:2023-07
- 期刊:
- 影响因子:3.2
- 作者:Markon, Andre O.;Ding, Ming;Chavarro, Jorge E.;Wolpert, Beverly J.
- 通讯作者:Wolpert, Beverly J.
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Jorge Eduardo Chavarro其他文献
Jorge Eduardo Chavarro的其他文献
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{{ truncateString('Jorge Eduardo Chavarro', 18)}}的其他基金
Childhood and Adult Psychosocial Stress and the Association with Disparities in Adult Cardiometabolic Health
儿童和成人心理社会压力以及与成人心脏代谢健康差异的关联
- 批准号:
10478317 - 财政年份:2019
- 资助金额:
$ 5.9万 - 项目类别:
Changes in Dietary Supplement Use During the COVID-19 Pandemic
COVID-19 大流行期间膳食补充剂使用的变化
- 批准号:
10281619 - 财政年份:2019
- 资助金额:
$ 5.9万 - 项目类别:
Integrating lifecourse approaches, biologic and digital phenotypes in support of heart and lung disease epidemiologic research
整合生命历程方法、生物学和数字表型以支持心肺疾病流行病学研究
- 批准号:
10620840 - 财政年份:2019
- 资助金额:
$ 5.9万 - 项目类别:
A lifecourse approach to women's cardiometabolic and bone health: from fertility to perimenopause
女性心脏代谢和骨骼健康的生命全程方法:从生育到围绝经期
- 批准号:
10378551 - 财政年份:2019
- 资助金额:
$ 5.9万 - 项目类别:
A lifecourse approach to women's cardiometabolic and bone health: from fertility to perimenopause
女性心脏代谢和骨骼健康的生命全程方法:从生育到围绝经期
- 批准号:
10728449 - 财政年份:2019
- 资助金额:
$ 5.9万 - 项目类别:
A lifecourse approach to women's cardiometabolic and bone health: from fertility to perimenopause
女性心脏代谢和骨骼健康的生命全程方法:从生育到围绝经期
- 批准号:
9975867 - 财政年份:2019
- 资助金额:
$ 5.9万 - 项目类别:
Integrating lifecourse approaches, biologic and digital phenotypes in support of heart and lung disease epidemiologic research
整合生命历程方法、生物学和数字表型以支持心肺疾病流行病学研究
- 批准号:
10116455 - 财政年份:2019
- 资助金额:
$ 5.9万 - 项目类别:
Integrating lifecourse approaches, biologic and digital phenotypes in support of heart and lung disease epidemiologic research
整合生命历程方法、生物学和数字表型以支持心肺疾病流行病学研究
- 批准号:
10487390 - 财政年份:2019
- 资助金额:
$ 5.9万 - 项目类别:
A lifecourse approach to women's mental health: from fertility to perimenopause
女性心理健康的生命全程方法:从生育到围绝经期
- 批准号:
10621562 - 财政年份:2019
- 资助金额:
$ 5.9万 - 项目类别:
A lifecourse approach to women's cardiometabolic and bone health: from fertility to perimenopause
女性心脏代谢和骨骼健康的生命全程方法:从生育到围绝经期
- 批准号:
10626721 - 财政年份:2019
- 资助金额:
$ 5.9万 - 项目类别:
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