Michigan Institute for Clinical and Health Research (MICHR)

项目摘要/摘要 密歇根临床与健康研究所(MICHR)催化临床和转化性研究 (CTR)和密歇根大学(U-M)的先进临床和翻译科学(CTS)，贯穿始终 密歇根州和全国。我们已经转变了密歇根大学的CTR，并一直是合作伙伴 与大学单位、密歇根社区以及临床和转化科学奖(CTSA) 财团。在接下来的七年里，MICHR将实现更大的创新、多样性、效率、公平、 CTR中的质量、包容性和覆盖范围，并开发、演示和传播可推广的CTS 创新。这一愿景包括五个战略目标：1)扩大推动战略 CTR和CTS的方向。我们将与我们的社区合作伙伴共同制定战略，以提升多样化 CTS领导层的声音。密歇根州社区公平审查委员会将确保社区的整合 在全州进行研究的声音和文化。患者即合作伙伴计划将使患者参与 学习发展和指导。2)将CTR推广到州，并增加与国家CTR的接触 通过CTS创新。我们将通过在全州范围内发展CTR能力来增加研究的机会。M- REACH平台将促进社区和学术的联系。网络接口将连接检查 团队、国家网络和大学合作伙伴。3)通过以下方式在CTR和CTS中吸引新团队 通道和支撑物。我们将通过新的培训、指导和指导来支持全州的CTR工作人员 课程、学徒制度和实践社区。我们将制定量身定做的研究培训计划 给以临床实践为重点的医生。研究团队将包括社区成员和患者，并将 由团队科学倡议和试点资助提供支持。4)通过传播和推广翻译 实施科学与应用。传播和实施催化剂将推动 传播和实施CTR和CTS的科学和应用。与我们的社区合作伙伴一起， 我们将共同开发工具，在公共卫生期间建立有效的学术和社区研究伙伴关系 紧急情况。我们将通过以人为中心的设计，将想法快速转化为可行的解决方案。 5)扩展MICHR服务，促进各类CTR的创新、质量和效率。我们会提供帮助的 学者和社区成员发展社区参与研究的科学技能。我们会 开发培训计划和工具，并扩展和调整我们的服务，以确保严格和高效 与健康相关的行为和社会科学研究。我们将为我们的电子医疗添加新的功能 记录搜索引擎和我们的参与者招募平台，以增加包容性。我们将确定成本- 改善方案质量策略的有效性和对临床试验绩效的影响。总而言之， MICHR准备进入其在密歇根州和全国推进CTR和CTS的第三个十年。

Project Summary/Abstract The Michigan Institute for Clinical & Health Research (MICHR) catalyzes clinical and translational research (CTR) and advances clinical and translational science (CTS) at the University of Michigan (U-M), throughout the state of Michigan, and nationally. We have transformed CTR at U-M and have been a collaborative partner with university units, Michigan communities, and the Clinical and Translational Science Award (CTSA) Consortium. In the next seven years, MICHR will achieve greater innovation, diversity, efficiency, equity, quality, inclusion, and reach in CTR and develop, demonstrate, and disseminate generalizable CTS innovations. This vision comprises five strategic goals: 1) Expand the diversity of voices driving the strategic direction of CTR and CTS. With our community partners, we will co-develop strategies to elevate diverse voices in CTS leadership. The Michigan Community Equity Review Board will ensure integration of community voice and culture in research throughout the state. The Patients as Partners Program will engage patients in study development and mentoring. 2) Extend CTR to the state and increase engagement with national CTR through CTS innovations. We will increase access to research by developing CTR capacity statewide. The M- REACH platform will facilitate community-academic connections. The Network Connector will connect study teams, national networks, and university partners. 3) Engage new groups in CTR and CTS through new pathways and supports. We will support the CTR workforce statewide through new trainings, mentoring programs, apprenticeships, and communities of practice. We will develop research training programs tailored to clinical practice-focused physicians. Study teams will include community members and patients and be supported by team science initiatives and pilot grant funding. 4) Extend translation through dissemination and implementation science and application. The Dissemination & Implementation Catalyst will advance the science and application of dissemination and implementation for CTR and CTS. With our community partners, we will co-develop tools for effective academic-community research partnerships during a public health emergency. We will enable rapid translation of ideas into actionable solutions through human-centered design. 5) Extend MICHR services to advance innovation, quality, and efficiency of diverse types of CTR. We will help academics and community members develop skills in the science of community-engaged research. We will develop training programs and tools as well as extend and adapt our services to ensure rigor and efficiency of health-related behavioral and social science research. We will add new features to our electronic medical record search engine and our participant recruitment platform to increase inclusivity. We will determine cost- effectiveness and effect on clinical trial performance of strategies for improving protocol quality. In summary, MICHR is poised to enter its third decade of advancing CTR and CTS throughout Michigan and the nation.