Administrative Core

项目摘要。行政核心构成了COBRE第三阶段神经可塑性中心的核心 在波多黎各大学。它支持这个COBRE中心的四重目标：1）招募和培养 培养从事与神经科学具有广泛生物医学相关性的项目的早期职业调查人员 和神经可塑性，2）升级，维护和促进最先进的仪器核心， 3）执行一项长期业务计划，以维持普遍定期审议， CcfN，神经成像和电生理设施（NIEF）的核心，以及促进 基础和翻译层面的多学科合作，4）维持全岛范围的全球公认的 COBRE神经可塑性中心，在神经退行性疾病和 神经发育障碍行政核心包含了这一举措的所有方案方面， 包括教师职业发展活动（实验室管理，拨款写作， 准备）和神经科学研究基础设施增强计划（研讨会系列， 驻场神经科学家，年度波多黎各神经科学会议，外展活动和学术 伙伴关系）。行政核心由一个由具有良好业绩记录的个人组成的团队组成， 具有大型多方面研究和培训项目的运营和管理经验。监督 是行政核心主任马克米勒博士的责任。米勒担任联络员， 计划及其评估模块，他协调与NIGMS官员的沟通。行政 支助办公室将继续配备一支经验丰富和敬业的团队，包括Bethzaida女士 Birriel，赠款管理员和Brenda卡班女士，会计师。所有财政事项都将在普遍定期审议中处理 分子科学资源中心（MSRC）和神经生物学研究所，两个独立的单位， 波多黎各大学。核心人员将处理授标后资金管理的大部分方面， 包括聘请技术人员，博士后和学生。最后，行政核心将协调所有 方案评估和评价，包括由一个独立的外部评价小组参与， Cooperativa de Servicios de Evaluación e Investigación（CoopSEI）。行政核心团队将组织 年度COBRE务虚会和评估活动，使所有利益相关者能够会面，交流想法， 报告进展，规划未来战略。这次会议将作为发展和 传播所有COBRE中心研究目标的形成性和总结性评估所需的数据 和方案举措。

Project Summary. The Administrative Core forms the nucleus of the COBRE Phase III Center for Neuroplasticity at the University of Puerto Rico. It supports the four-fold objectives of this COBRE Center: 1) Recruit and foster development of early career investigators working on projects with broad biomedical relevance to neuroscience and neuroplasticity, 2) Upgrade, maintain, and promote a state-of-the-art instrumentation core that combines imaging and electrophysiological approaches, 3) Implement a long-term business plan that will sustain the UPR- CCfN, the Neuroimaging and Electrophysiology Facility (NIEF) core, and programmatic activities that promote multidisciplinary collaborations at the basic and translational levels, 4) Sustain an island-wide globally recognized COBRE Center for Neuroplasticity with translational and therapeutic applications to neurodegenerative and neurodevelopmental disorders. The Administrative Core incorporates all programmatic facets of this initiative, including Faculty Career Development Activities (Laboratory Management, Grant Writing, Manuscript Preparation) and Neuroscience Research Infrastructure Enhancement programs (Seminar Series, Neuroscientist-in-Residence, Annual Puerto Rico Neuroscience Conference, Outreach Activities, and Academic Partnerships). The Administrative Core is composed of a team of individuals with proven track records and experience in the operation and management of large multi-faceted research and training programs. Oversight is the responsibility of the Administrative Core Director, Dr. Mark Miller. Miller serves as liaison between the program and its Evaluation Module and he coordinates communication with NIGMS officials. The Administrative Support Office will continue to be staffed by a highly experienced and dedicated team, including Ms. Bethzaida Birriel, Grants Administrator and Ms. Brenda Caban, Accountant. All fiscal matters will be managed at the UPR Molecular Sciences Resource Center (MSRC) and at the Institute of Neurobiology, two freestanding units of the University of Puerto Rico. Core personnel will handle most aspects of the post-award administration of funds, including hiring of technicians, postdocs, and students. Finally, the Administrative Core will coordinate all program appraisal and assessment, including the participation of an independent external evaluation team from Cooperativa de Servicios de Evaluación e Investigación (CoopSEI). The Administrative Core team will organize the Annual COBRE Retreat and Assessment Activity that will enable all stakeholders to meet, exchange ideas, report progress, and plan future strategies. This meeting will serve as the principal forum for developing and disseminating data required for formative and summative evaluation of all COBRE Center research objectives and programmatic initiatives.