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Predoctoral Training in Multifaceted Translational Approach to Mental Illness

Predoctoral Training in Multifaceted Translational Approach to Mental Illness
精神疾病多方面转化方法的博士前培训
批准号:
10628129
负责人:
Yogesh Dwivedi
金额:
$8.4万
依托单位国家:
美国
项目类别:
财政年份:
2023
资助国家:
美国
项目状态:
未结题
起止时间:
2023-06-01 至 2028-05-31

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中文摘要
翻译
精神障碍是造成残疾的最常见原因之一,疾病负担也是最高的 所有的疾病。因此,不仅迫切需要开发新的治疗方法,而且还迫切需要开发下一种治疗方法。 培养一代能够应对日益增长的心理健康研究领域挑战的研究科学家。 这个“精神疾病多方面转化方法的博士前培训”的总体目标 (AMI)“计划(Adrienne拉赫蒂,医学博士和Yogesh Dwivedi,博士担任董事)是为学生提供一个 跨文化培训的环境,他们将接触到临床挑战,生物 机制,和尖端的研究方法用于精神疾病,而不是那种单一的, 他们可能通过在个人研究实验室工作获得的疾病培训。AMI T32培训计划 将独特地提供一个跨学科的培训环境,将整合基础和转化研究 培养博士前学生培养批判性思维的发展,沟通,并深入 研究技能。建立在坚实的基础上,并由优秀的基础设施的大型基础设施支持, 翻译和多学科的精神卫生研究计划,AMI培训计划将采取 跨学科的心理健康研究调查工作的优势,由强大的,国际知名的 UAB精神病学系内的临床和教育资源,动态心理健康研究 综合神经科学中心的努力,UAB的大学范围内的跨学科倡议 抑郁症和自杀中心,综合转化科学中心和UAB毕业生 基于主题的研究生生物医学科学和心理学博士课程内的课程 隶属于心理学系UAB的协作环境,由各种核心体现, 中心,计划和部门将为振兴研究工作提供广泛的支持。培训 该计划要求每年三个博士前培训名额,并将利用完善的最佳 成功征聘代表性不足的少数群体和残疾人的做法。该计划 将包括必要的教学课程,实验室和临床研究,期刊俱乐部,研讨会,科学 在地方和国家会议上介绍情况,并进行负责任地开展研究的培训。学员 还将受益于赠款写作和专业技能发展课程。学员和 指导团队将制定个人发展计划。内部和外部咨询委员会将 评估AMI培训计划的整体绩效。一系列衡量进展的基准将是 为每个受训者和指导者制定,并每半年审查一次。作为美国国立卫生研究院资助的前25名学术机构, 医学中心拥有最先进的科学核心设施和大学范围内的跨学科研究中心, 位于伯明翰的亚拉巴马大学在培养新一代 将推动和改变心理健康研究的转化科学家。
英文摘要
Mental disorders are among the most common causes of disability, and the disease burden is among the highest of all illnesses. Thus, there is an urgent need to develop not only novel therapeutic approaches but also the next generation of research scientists who can meet the challenges of the growing field of mental health research. The overarching goal of this “Predoctoral Training in a Multifaceted Translational Approach to Mental Illness (AMI)” program (Adrienne Lahti, MD, and Yogesh Dwivedi, PhD as Directors) is to provide the students with an environment of cross-cultural training where they will be exposed to the clinical challenges, biological mechanisms, and cutting-edge research approaches used across mental illnesses, rather than the kind of single- disease training they might obtain by working in an individual research laboratory. The AMI T32 training program will uniquely provide an interdisciplinary training environment that will integrate basic and translational research training of predoctoral students to foster the development of critical thinking, communication, and in-depth research skills. Built on a strong foundation and supported by a large infrastructure of outstanding basic, translational, and multidisciplinary programs in mental health research, the AMI training program will take advantage of interdisciplinary mental health research investigative efforts led by strong, internationally renowned clinical and educational resources within the UAB Department of Psychiatry, dynamic mental health research efforts by the Comprehensive Neuroscience Center, university-wide interdisciplinary initiatives of the UAB Depression and Suicide Center, the Comprehensive Center for Translational Sciences, and UAB graduate programs within the thematically based Graduate Biomedical Sciences and the Psychology Doctoral Program affiliated with the Department of Psychology. The collaborative environment at UAB, embodied by various cores, centers, programs, and departments, will provide extensive support for invigorating research efforts. The training program is requesting three predoctoral training slots per year and will take advantage of well-established best practices for the successful recruitment of underrepresented minorities and individuals with disabilities. The plan will include required didactic courses, laboratory and clinical research, journal clubs, seminars, scientific presentations both locally and at national meetings, and training in the responsible conduct of research. Trainees will also benefit from courses on grant writing and professional skills development. Together, the trainee and mentoring team will craft an individual development plan. Internal and External Advisory Committees will evaluate the overall performance of the AMI training program. A series of benchmarks for progress will be formulated for each trainee and mentor and reviewed on a semi-annual basis. As a top 25 NIH-funded academic medical center with state-of-the-art scientific core facilities and university-wide, interdisciplinary research centers, the University of Alabama at Birmingham is remarkably well-positioned to cultivate a new generation of translational scientists who will advance and transform mental health research.
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会议论文
Neural-Derived Plasma Exosomal MicroRNAs As Promising Novel Biomarkers for Suicidality and Treatment Outcome in Adolescents
Novel regulatory role of nuclear miRNAs in repatterning the transcriptional and post-transcriptional dynamics in MDD brain
MicroRNA Correlates of Childhood Maltreatment and Suicidality
MicroRNA Correlates of Childhood Maltreatment and Suicidality
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