Research Training in Systems Skin Biology

项目总结/摘要 这个新的T32应用程序题为研究培训系统皮肤生物学是一个结合前和后， 博士培训计划（MPI金和米勒共同PD）。这一建议的理由是，伊坎学校的 西奈山医学（ISMMS）在皮肤病学，皮肤免疫学和上皮细胞免疫学方面取得了成功。 生物学，以便它可以利用额外的机构优势（例如，神经科学，转化医学， 等等）。建立一个跨学科的系统皮肤生物学培训计划。核心假设是， 交叉科学对于培养未来的科学家在单一器官系统中至关重要， 皮肤最后，我们在以正规的方式培养物理学家和科学家的能力方面存在重大差距， T32将提供一个成功的平台。该计划的总体目标是吸引和培训 有才华的MD/PhD和PhD学生和博士后超过2年的时间，在 与人类疾病相关的系统皮肤生物学。我们有一个多元化，资金充足的教师与广泛的兴趣， 系统皮肤生物学在免疫学和一个强大的池前和博士后学员，其中包括重要的 科学少数民族（UiS）人数不足。该方案旨在通过以下方式提供培训： 在与人类疾病相关的系统皮肤生物学的各个方面进行研究的个人导师。的 该计划得到了强有力的监督和行政结构的支持，在系统中进行了重要的教学培训 皮肤生物学，科学写作和职业发展，并包含新增加的最先进的评估状态 有明确的目标和成功的基准，以优化独立的发展， 该领域的学术研究人员。该计划的长期目标是培养1名MD/PhD或PhD科学家 在调查皮肤病学/皮肤生物学研究每2年谁成为独立资助通过K或 R机制。

PROJECT SUMMARY/ABSTRACT This new T32 application entitled Research Training in Systems Skin Biology is a combined pre- and post- doctoral training program (MPIs Kim and Millar Co-PDs). The rationale for this proposal is that Icahn School of Medicine at Mount Sinai (ISMMS) has a track record of success in dermatology, skin immunology, and epithelial biology such that it can leverage additional institutional strengths (e.g., neuroscience, translational medicine, etc.) to build an interdisciplinary training program in Systems Skin Biology. The central hypothesis is that such intersectional science is critically important for the training of future scientists within single organ systems like the skin. Finally, there is a major gap in our ability to train physician-scientist in a formalized manner which this T32 would provide a platform to do successfully. The overall objective of this program is to attract and train talented MD/PhD and PhD students and postdocs over 2 year periods, for successful, independent careers in Systems Skin Biology relevant to human disease. We have a diverse, well-funded faculty with broad interests in Systems Skin Biology in immunology and a strong pool of pre- and post-doc trainees that includes significant numbers of underrepresented in science (UiS) minorities. The program is designed to provide training by individual mentors performing research in all aspects of Systems Skin Biology relevant to human disease. The program is supported with strong oversight and administrative structure, significant didactic training in Systems Skin Biology, scientific writing and career development, and contains newly added state of the art evaluation approaches with defined goals and benchmarks for success so as to optimize the development of independent academic researchers in the field. The long-term goal of this program is to produce 1 MD/PhD or PhD scientist in investigative dermatology/skin biology research every 2 years who become independently funded via a K or R mechanism.